Results 81 to 90 of about 27,924,758 (382)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Air handling system optimisation [PDF]

open access: yes, 1991
Often each floor of a building has an air handling system consisting of a plant room, ducting and equipment such as fans and heaters. The cost of the system consists of the capital cost of the equipment and the operating cost to satisfy the thermal loads.
Mills, G.
core  

The structure of an operating system [PDF]

open access: yes, 1976
This paper describes the use of the class and inner concepts of SIMULA 67 to express the multi-level structure of an operating system. A comparison is drawn between compile-time checking and run-time protection.
openaire   +3 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Sequentialized Virtual File System: A Virtual File System Enabling Address Sequentialization for Flash-Based Solid State Drives

open access: yesComputers
Solid-state drives (SSDs) are widely adopted in mobile devices, desktop PCs, and data centers since they offer higher throughput, lower latency, and lower power consumption to modern computing systems and applications compared with hard disk drives (HDDs)
Inhwi Hwang   +3 more
doaj   +1 more source

Wireless Sensor Network Operating System Design Rules Based on Real-World Deployment Survey

open access: yesJournal of Sensor and Actuator Networks, 2013
Wireless sensor networks (WSNs) have been a widely researched field since the beginning of the 21st century. The field is already maturing, and TinyOS has established itself as the de facto standard WSN Operating System (OS).
Leo Selavo   +3 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Data‐driven performance metrics for neural network learning

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri   +2 more
wiley   +1 more source

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