Results 81 to 90 of about 932,981 (241)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Docker Performance Evaluation across Operating Systems

open access: yesApplied Sciences
Docker has gained significant popularity in recent years. With the introduction of Docker Desktop for Windows and macOS, there is a need to determine the impact of the operating system on the performance of the Docker platform.
Maciej Sobieraj, Daniel Kotyński
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Key aspects of the modern paradigm of operational management

open access: yesAgricultural and Resource Economics, 2018
Purpose. The purpose of the article is to present a modern paradigm of operational management by refining its characteristic moments in view of the genesis of management science and the development of modern technologies and business tools.
Alexander Sumets
doaj  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Methodological approach to quantitative assessment of the security of open operating systems AS of the Internal Affairs Bodies

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The article considers the provisions of the fuzzy logic approach in relation to the method of quantifying the security of open operating systems (OS) of automated systems of the internal affairs bodies of the Russian Federation (AS of the ...
A. I. Yangirov   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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