Results 81 to 90 of about 20,166,974 (303)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

FY2010 Operating Budget and Student Charges [PDF]

open access: yes, 2008
The University of Maine System operating budget and proposed student charges ...
University of Maine System
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Review of operating systems used in unmanned aerial vehicles

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
Operating systems (OS) play a major role in the functionality and performance of unmanned aerial vehicles, serving as their central nervous system to manage various components and functions.
Viktor Ivashko   +3 more
doaj   +1 more source

FY2008 Operating Budget and Student Charges [PDF]

open access: yes, 2007
The University of Maine System operating budget and proposed student charges ...
University of Maine System
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

An empirical assessment of the impact of network effects on competitive processes in the operating systems market

open access: yesУправленец
Modern technology markets are characterized by the presence of a network effect, a phenomenon that significantly affects network adoption. While providing the advantage of belonging to a network, network effects can curb the diffusion of alternative ...
Viktoria S. Bogolyubova
doaj   +1 more source

A new general-purpose operating system

open access: yes, 1987
The current generation of widely-used, multi-user, general-purpose operating systems have evolved from versions that were designed when many of the issues that are important today were unimportant or not even thought of.
Venter, BH
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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