Results 91 to 100 of about 3,255,827 (300)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2022 In this chapter, we will provide a description of existing open-source operating systems (OSs) which have been analyzed with the objective of providing a porting for the reference architecture described in Chapter 2. Among the various possibilities, the ERIKA Enterprise RTOS (Real-Time Operating System) and Linux with preemption patches have been ...
Scordino C. +5 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Effect of Business Operating Systems on Nursing Home Termination. [PDF]
Int J Public Health, 2023 Jin X +7 more
europepmc +1 more source
Towards quantification of condition monitoring benefit for wind turbine generators [PDF]
, 2007 Condition monitoring systems are increasingly installed in wind turbine generators with the goal of providing component-specific information to the wind farm operator and hence increase equipment availability through maintenance and operating actions ...
Ault, G.W., Mcmillan, David
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Hopes and facts in evaluating the performance of HPC-I/O on a cloud environment
Journal of Computer Science and Technology, 2015 Currently, there is an increasing interest about the cloud platform by the High Performance Computing (HPC) community, and the Parallel I/O for High Performance Systems is not an exception.
Pilar Gómez Sánchez +3 more
doaj
Research on the brand image of iOS and Android smart phone operating systems based on mixed methods. [PDF]
Front Psychol, 2023 Hu W +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source