Results 61 to 70 of about 14,926,412 (344)

Modeling and Analysis of Drill String–Casing Collision under the Influence of Inviscid Fluid Forces

open access: yesApplied Sciences, 2023
The current study aims to study the drill string–casing system operating in an inviscid fluid under imbalanced and rubbing damage types. The Navier–Stokes equations were linearized to establish the hydrodynamic forces surrounding the drill string and ...
Bernard Xavier Tchomeni Kouejou   +2 more
doaj   +1 more source

Performance Evaluation of Fuel Cell and Microturbine as Distributed Generators in a Microgrid [PDF]

open access: yes, 2009
This paper presents dynamic models of distributed generators (DG) and investigates dynamic behaviour of the DG units within a microgrid system. The DG units include micro turbine, fuel cell and the electronically interfaced sources.
Mohamed , Azah   +2 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A Method for Determining the Usability Potential of Ship Steam Boilers

open access: yesPolish Maritime Research, 2016
Ship large-power steam boiler may serve as an example of complex critical technical system. A basis for rational control of operation of such system is knowledge on its capability of fulfilling the tasks to which it was intended.
Muślewski Łukasz   +3 more
doaj   +1 more source

A Hybrid Optimization Method Combining Network Expansion Planning and Switching State Optimization

open access: yesIEEE Open Access Journal of Power and Energy, 2020
Combining switching state optimization (SSO) and network expansion planning (NEP) in AC systems results in a mixed-integer non-linear optimization problem. Two methodically different solution approaches are mathematical programming and heuristic methods.
Florian Schafer   +2 more
doaj   +1 more source

The Evolution of OSI Network Management by Integrated the Expert Knowledge [PDF]

open access: yes, 2006
The management of modern telecommunications networks must satisfy ever-increasing operational demands. Operation and quality service requirements imposed by the users are also an important aspect to consider.
León de Mora, Carlos   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Who is Facing Higher Increased Demand After the Online-Offline Channel Integration? Evidence from Public Hospitals in China

open access: yesRisk Management and Healthcare Policy, 2023
Heng Zhao, Xuejing Cao School of Economics and Management, Tongji University, Shanghai, 200092, People’s Republic of ChinaCorrespondence: Xuejing Cao, School of Economics and Management, Tongji University, 1239 Siping Road, Yangpu District, Shanghai ...
Zhao H, Cao X
doaj  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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