Results 121 to 130 of about 6,223 (252)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Operational amplifier having an adjustable frequency compensation

open access: yes, 1998
An integrated operational amplifier with adjustable frequency compensation having a transconductance input stage and an amplifier output stage connected serially together between an input terminal and an output terminal of the operational amplifier.
G. Clerici   +3 more
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Design of the Rail-to-Rail operational amplifier in CMOS

open access: yes, 2016
This thesis deals with design of rail-to-rail class AB operational amplifier in CMOS technology I3T25. Starting with a short introduction to CMOS transistors, following with description of operational amplifier, structures of operational amplifier, its ...
Cvešper, Stanislav
core  

An improved voltage measuring method for single battery in series batteries

open access: yesGong-kuang zidonghua, 2013
In view of problem of leakage current in voltage measuring method for single battery in series batteries based on operational amplifier and MOSFET, an improved voltage measuring method was proposed.
LIN Yin, DENG Fei, LIU Ya-hui
doaj  

Influence of the Gain–Bandwidth of the Front-End Amplifier on the Performance of a QEPAS Sensor

open access: yesAcoustics
The quartz tuning fork used as an acoustic sensor in quartz-enhanced photo-acoustic spectroscopy gas detection systems is usually read out by means of a transimpedance preamplifier based on a low-noise operational amplifier closed in a feedback loop. The
Luigi Lombardi   +2 more
doaj   +1 more source

CMOS operational amplifier with nearly constant settling time

open access: yes, 2022
S.309-314An operational amplifier with a settling time nearly independent of the signal amplitude and the capacitive load has been realised in CMOS technology.
Klinke, R.   +3 more
core  

Design of the operational amplifier offset auto-compensation

open access: yes, 2014
This work deals with the two-stage operational amplifier with automatic offset compensation. An operational amplifier is designed in Cadence design environment for possible implementation in technology CMOS07. Emphasis work is placed on minimum offset of
Dula, Přemysl
core  

Limit circuit prevents overdriving of operational amplifier

open access: yes, 1967
Cutoff-type high gain amplifier coupled by a diode prevents overdriving of operational amplifier. An amplified feedback signal offsets the excess input signal that tends to cause the amplifier to exceed its preset limit.
Openshaw, F. L.
core   +1 more source

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