Results 151 to 160 of about 6,223 (252)

Design of operational amplifier using telescopic structure

open access: yes, 2012
The work deals with design and function verification of the telescopic operational ...
Komár, Karel
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

A universal CMOS current-mode operational amplifier

open access: yes
It has become customary in electrical engineering to think of signal processing in terms of voltage variables to the exclusion of current variables.
Botelho, Cindy
core   +1 more source

Operational amplifier of very small measurable signals

open access: yes, 2019
Diplomska naloga obravnava snovanje in izgradnjo operacijskega ojačevalnika s spremenljivim ojačenjem, ki seže vse do vrednosti 10,000. Ojačevalnik je namenjen merjenju zelo šibkih signalov.
Gams, Matej
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

The design, fabrication, and test of a CMOS operational amplifier

open access: yes, 1990
The topic of this thesis is the design, fabrication, and testing of a CMOS operational Amplifier. This Operational Amplifier was first realized as a class design project for Advanced Analog IC design.
Sayre, Edward P.
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Autocompensation of operational amplifier offset for precise measurement

open access: yes, 2009
This work deals with the problems of the design of two stage operational amplifier with automatic offset compensation for precise measurement. Full design operational amplifier is aimed at appropriate realization in technology CMOS07 with usage Cadence ...
Prášek, David
core  

Home - About - Disclaimer - Privacy