Results 241 to 250 of about 97,874 (341)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Light-insensitive organic solar-powered amplifiers. [PDF]

Nat Commun
Wu Q, Wang S, Gao W, Chen Z, Tao J, Song X, Yan S, Zhu H, Zhou K, Jiang L, Xu X, Jen AK, Ma W.   +12 more
europepmc   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Lab-on-PCB with integrated DNA amplification and electroanalytical detection for point-of-care diagnostics. [PDF]

Sci Rep
Thorapalli Muralidharan S, Hanze M, Ainla A, Möller B, Hamedi MM, Toldrà A.   +5 more
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Modeling and Experimental Analysis of Hybrid Cantilever Structures with Embedded MFC Patch. [PDF]

Materials (Basel)
Mitura A.
europepmc   +1 more source

A Low Power Low Noise Chopper-Stabilized Tow-stage Operational Amplifier for Portable Bio-potential Acquisition Systems Using 90 nm Technology

, 2014
Fateh Moulahcene, Nour-Eddine Bouguechal, Youcef Belhadji   +2 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

<i>OpenCHIRP</i>: A Low-Cost, Lightweight Sub-Bottom Profiler for Shallow Water Environments Suitable for Autonomous Vehicles. [PDF]

Sensors (Basel)
Stanghellini G, Del Bianco F, Suriano F, Gasperini L.   +3 more
europepmc   +1 more source