Results 141 to 150 of about 1,419,236 (288)

Computational and Data‐Driven Strategies for Lignocellulosic Biomass Valorization: From Multiscale Modeling to Digitalized Biorefinery Design

Advanced Science, EarlyView.
This Review critically connects structural recalcitrance, molecular modeling, solvent and catalyst design, pyrolysis, machine learning, reactor simulation, and FAIR digital infrastructure. Emphasis is placed on experimentally validated information transfer across scales, uncertainty and applicability domains, and the recycle, durability, techno ...
Abdullahi Bello Umar, Jiaxian Zheng, Xiangfeng Lin, Hongwu Liao, Haoqian Xu, Yufei Huang, Zaharaddeen Nasiru Garba, Adamu Uzairu, Weiwei Zhao, Zhanhui Yuan   +9 more
wiley   +1 more source

Morphology‐Defined Entropy Streams for Random‐Bit Generation and Probabilistic Sampling in Memristor Arrays

Advanced Science, EarlyView.
Au nanoisland morphology defines stochastic high‐resistance‐state transport in Ag/TiO2 memristor arrays, transforming nanoscale structural disorder into a tunable physical entropy resource. Morphology‐controlled field hotspots and reset‐modulated nanogaps generate statistically validated random‐bit streams, which further serve as device‐derived ...
Hyunjun Kim, Da Ye Kim, Noah Jang, Yongho Lee, Byunghun Song, June Soo Kim   +5 more
wiley   +1 more source

Beyond Blind Trust in Hospital Data Warehouses: Evaluating Real-World Data Accountability. [PDF]

Learn Health Syst
Morohashi A, Yamashita S, Imaizumi T, Sano T, Kuwatsuka Y, Ando M, Shiratori Y.   +6 more
europepmc   +1 more source

Orthogonal Light‐ and Enzyme‐Triggered and‐Gate Prodrugs for Senolytic Therapy

Advanced Science, EarlyView.
An orthogonal AND‐gate prodrug platform combines 390 nm near‐UV photocleavage with SA‐β‐gal activation to control payload release in senescent cells. Its modular architecture enables 4‐MU fluorescence, doxorubicin‐mediated cytotoxicity, and ARV‐771‐driven BRD4 degradation, supporting stimulus‐controlled senolytic design in cellular and organoid models.
Mengyang Chang, Kaixue Zhang, Junwei Wang, Fangchao Bi, Zhuoxin Dai, Miao Yang, Ming Liu, Huanzhi Peng, Franklin Zhang, Yuan Guo, Jigang Dai, Quanxing Liu, Wei Wang   +12 more
wiley   +1 more source

Continuous assurance for AI-driven clinical decision support systems. [PDF]

Front Artif Intell
Al-Horani RA, Tadesse AF.
europepmc   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

Advanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo, Katie Shi, Lina Kafadarian, Alexandra Bermudez, Johnny Diaz, Liam Edwards, Yunqi Hong, Ziyi Chen, Hyeonji Hwang, Weihong Yan, Alan Levinson, Robert Damoiseaux, Cho‐Jui Hsieh, Tanya Stoyanova, Andrew S. Goldstein, Neil Y.C. Lin   +15 more
wiley   +1 more source

Financial and compliance audit report: State of Kansas Fiscal Year 2010

, 2011
application/pdf; "February 2011."; "A Report to the Legislative Post Audit Committee" ...
Allen, Gibbs & Houlik.
core  

Climate Change is Rewriting the Hydroclimatic Operating Envelope of Mines

Advanced Science, EarlyView.
Climate change is shown to shift the hydroclimatic operating envelope of mines: 16.2% of represented mine locations have already changed Köppen subtype, rising to 42.5% by late century under SSP5‐8.5. Divergent water trajectories are filtered through geology, infrastructure and lifecycle stage, indicating that adaptation requires monitored, scenario ...
Haoxuan Yu, Izni Zahidi, Chow Ming Fai, Jilong Pan   +3 more
wiley   +1 more source

LATTICE: a governance-first architecture for authorized autonomous AI operations. [PDF]

Front Artif Intell
Calboreanu E.
europepmc   +1 more source

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

Advanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen, Zhenguo Cao, Zenan Wang, Liang Chen, Jiahao Zhang, Linjie Zeng, Boren Tan, Hengyuan Li, Jiashan Lai, Jiangchu Lei, Fanglu Chen, Peng Lin, Zhenxuan Shao, Zhan Wang   +13 more
wiley   +1 more source