Results 261 to 270 of about 86,734 (328)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research. [PDF]

Data Brief
Standeven FJ, Dahlquist-Axe G, Hendy J, Fiddyment S, Holst M, McGrath K, Collins M, Mundorff A, Radini A, Wagner J, Meehan CJ, Tedder A, Speller CF.   +12 more
europepmc   +1 more source

The operational calculus

Mathematische Annalen, 1926
openaire   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

How external stimuli drive physicians' value co-creation behavior in online health communities: the mediating role of risk-benefit perceptions and moderating role of digital competency. [PDF]

Front Public Health
Yao Y, Cao J, Wang J, Zhong Y, Feng M.
europepmc   +1 more source

Non-interleaving Operational Semantics for the Pi-calculus - technicalities

, 2016
Christian Johansen, Håkon Norman, Thomas Hildebrandt   +2 more
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Robust direct voltage control of stand-alone DFIG wind systems using a fractional-order fuzzy logic approach. [PDF]

Sci Rep
Boucetta F, Alturki M, Albaker A, Alqunun K, Benchouia MT, Alshammari BM, Becherif M, Guesmi T.   +7 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Human calculus adhesive-induced periodontitis model recapitulating human periodontitis microbiota in rats. [PDF]

BMC Oral Health
You Y, Wu HL, Chen DY, Yu SY, Xu Y, Tang Y, Sun HL, Huang C.   +7 more
europepmc   +1 more source