Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
An operational super-pressure balloon system to carry 50 pounds to 10 millibar atmospheric pressure Final report [PDF]
Design considerations for development of operational super-pressure balloon system to carry 50 pounds to 10 millibar atmospheric ...
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Application of the funding GAP method in the process of financing regional development in Romania [PDF]
The present paper aims at analyzing the framework and the methodology for applying the funding gap method in order to determine the level of structural funds co-financing in the process of financing regional development in Romania, through the Regional ...
Oana GHERGHINESCU
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
OPERATIONAL PROGRAMME - DEVELOPMENT OF EASTERN POLAND, 2007 – 2013. DEVELOPMENT OPPORTUNITIES OF LUBLIN VOIVODESHIP AND THE INSTRUMENT OF REGIONAL CONVERGENCE [PDF]
The entire European Union is made up of the elements characterized by, among others, different level of economic development. So far, a measure of the level of the development is Gross Domestic Product per capita.
Magdalena Czerwiñska
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The DOE/NASA wind turbine data acquisition system. Part 3: Unattended power performance monitor [PDF]
Software documentation, operational procedures, and diagnostic instructions for development version of an unattended wind turbine performance monitoring system is provided. Designed to be used for off line intelligent data acquisition in conjunction with
Halleyy, A. +3 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Identifying Key Indicators and Components of Earthquake Preparedness Exercises in the Prehospital Setting: An Exploratory Content Analysis From Paramedic Nurses' Perspectives. [PDF]
Nurs Res PractAminafshar A +6 more
europepmc +1 more source