Results 61 to 70 of about 409,532 (317)
Operational Risk Management [PDF]
We view risk management as an integral part of good management. Risk management should take a balanced view of decision problems encompassing all significant risks and rewards. Operational risks are only one type of risks and therefore are only one piece
Jacques Pezier
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
An Aggregated Information Technology Checklist for Operational Risk Management [PDF]
This study addresses the issue of the Information Technology (IT) Governance frameworks and standards that respond to different levels of operational risks, especially those caused by the information systems and technology infrastructure.
Mehmet Zeki Önal
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Waking the sleeping giant: Maximising the potential of operational risk management for banks
, 2011 Within the banking sector operational risk is often perceived to be a less important risk than financial risks such as market or credit risk. Such a view is typically reinforced by the observation that banks are in the business of taking these financial ...
Thirlwell, John +2 more
core
Firm Value and the Impact of Operational Management [PDF]
, 2019 Operational management has been gaining increasing importance in the financial industry and firms make substantial investments in operations management systems to reduce operational risk.
Mitra, S. +5 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Basel II and Operational Risk: Implications for risk measurement and management in the financial sector [PDF]
This paper proposes a methodology to analyze the implications of the Advanced Measurement Approach (AMA) for the assessment of operational risk put forward by the Basel II Accord.
Yves Crama +3 more
core
Category management for the operational resource procurement
Journal of Innovation & KnowledgeThe introduction of Category Management in operational resources purchasing helps to improve logistics service levels and increase the profitability of industrial enterprises. There are two main purposes of the provided article.
Ivan Elyashevich +3 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source