Results 111 to 120 of about 701,369 (343)
پژوهشهای ریاضی, 2019 Introduction A system of integral equations can describe different kind of problems in sciences and engineering. There are many different methods for numerical solution of linear and nonlinear system of integral equations. Material and methods This paper
Elnaz Babaei, Elham Hashemizadeh
doaj
QUASI-EXACTLY SOLVABLE MATRIX SCHRÖDINGER OPERATORS [PDF]
Modern Physics Letters A, 2000 Two families of quasi-exactly solvable 2×2 matrix Schrödinger operators are constructed. The first one is based on a polynomial matrix potential and depends on three parameters. The second is a one-parameter generalization of the scalar Lamé equation. The relationship between these operators and QES Hamiltonians already considered in the literature is
openaire +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Journal of Mathematical Sciences and Modelling, 2018 In this paper, we consider a spectral method to solve a class of two-dimensional singular Volterra integral equations using some basic concepts of fractional calculus.
Somayeh Nemati
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Mathematical Modelling and AnalysisWe consider the discretization method for solving three-dimensional variable-order (3D-VO) time-fractional partial differential equations. The proposed method is developed based on discrete shifted Hahn polynomials (DSHPs) and their operational matrices.
Haniye Dehestani +2 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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