FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
A Method for the Intelligent Identification of the Operating Conditions of Deep-Sea Submersibles and Its Application. [PDF]
Sensors (Basel)Zhang Y, Li Z, Tang J, He K.
europepmc +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Lean Six Sigma for Sharps Waste Management and Occupational Biosafety in Emergency Care Units. [PDF]
Int J Environ Res Public HealthAyres MAC +4 more
europepmc +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
AI-enhanced multi-timescale optimization strategy for virtual power plants: Advancing losad forecasting and dynamic demand response integration. [PDF]
PLoS OneXu G +5 more
europepmc +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Robust modeling and evidence-based evaluation method for a active distribution network with EVs and CHPs. [PDF]
Sci RepChen K, Yuan J, Fang Z, Mao Y.
europepmc +1 more source
Novel derivative operational matrix in Caputo sense with applications [PDF]
Danish Zaidi +3 more
openalex +1 more source
Risk Assessment Matrix of Operational Safety (RAMOS): Aviation Safety with a MATLAB® Design Toolkit
, 2023 Haoruo Fu, Chien-tsung Lu, Zhenglei Ji
openalex +1 more source