Results 151 to 160 of about 1,117,343 (309)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Comparing manned to unmanned aerial surveys for cetacean monitoring in the Arctic: methods and operational results [PDF]

, 2018
Robyn P. Angliss, Megan C. Ferguson, Philip Hall, V. T. Helker, Amy S. Kennedy, Todd L. Sformo   +5 more
openalex   +1 more source

A Weekly Indicator of Surface Moisture Status from Satellite Data for Operational Monitoring of Crop Conditions. [PDF]

Sensors (Basel), 2017
Nutini F, Stroppiana D, Busetto L, Bellingeri D, Corbari C, Mancini M, Zini E, Brivio PA, Boschetti M.   +8 more
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

A NOVEL COMBINED CHAOS-GEOMETRIC AND VIBRATION BLIND SOURCE MONITORING APPROACH TO DAMAGE ANALYSIS AND DETECTION OF ENGINEERING STRUCTURES (NUCLEAR POWER PLANTS) UNDER VARYING ENVIRONMENTAL, OPERATIONAL CONDITIONS AND EMERGENCY ACCIDENTS

, 2017
V. V. Buyadzhi, А. В. Глушков, M. Yu. Gurskaya, О. Yu. Khetselius, E. B. Ternovsky, A. A. Mashkantsev, S. V. Kirianov   +6 more
openalex   +2 more sources

Continuous seismic threshold monitoring of the northern Novaya Zemlya test site; long-term operational characteristics

, 2023
Tormod Kværna
openalex   +1 more source

Operational Modal Analysis and Structure Health Monitoring [PDF]

, 2021
Roberta Lima
openalex   +1 more source

Architecture and Information Requirements to Assess and Predict Flight Safety Risks During Highly Autonomous Urban Flight Operations [PDF]

As aviation adopts new and increasingly complex operational paradigms, vehicle types, and technologies to broaden airspace capability and efficiency, maintaining a safe system will require recognition and timely mitigation of new safety issues as they ...
Ancel, Ersin, Corbetta, Matteo, Darafsheh, Kaveh, Dill, Evan, Evans, Emory, Foster, John, Kulkarni, Chetan, Moore, Andrew, Okolo, Wendy, Ossenfort, John, Quach, Cuong, Smalling, Kyle, Spirkovska, Lilly, Vazquez, Sixto, Watkins, Jason, Young, Steven   +15 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Predictive monitoring of asset populations in a rotating plant under operational uncertainty: a transfer learning approach [PDF]

Ziad G. Ghauch, Andrew Young, Blair Brown, Bruce Stephen, Graeme West, S.D.J. McArthur, A. Duncan   +6 more
openalex   +1 more source