Results 231 to 240 of about 5,293,051 (299)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

ML-Based Framework for Urban Thermal Comfort Measurement and Climate Adaptation: Case Study of Barcelona. [PDF]

Sensors (Basel)
Cipollone V, Serroni S, Cecconi N, Federici E, Morresi N, Mor G, Revel GM.   +6 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Software-Defined UHF RFID Asset Tracking in Metallic Aircraft Cabins via IMU-Assisted Adaptive Kalman Filtering and Distilled Edge Intelligence. [PDF]

Sensors (Basel)
Karadag M, Pinarer O.
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Certification Criteria and Bio-Inspired Functional Themes: LEED v5 and BREEAM V7 Profiles with a Bounded YeS-TR Audit. [PDF]

Biomimetics (Basel)
Yılmaz E, Akkam MS.
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Daily emergency department volume and in-hospital mortality: the importance of temporal alignment. [PDF]

Scand J Trauma Resusc Emerg Med
Gültekin M.
europepmc   +1 more source

Governing accelerated evidence in real-time clinical trials. [PDF]

Commun Med (Lond)
Seixas AA.
europepmc   +1 more source

Real-Time Dynamic Adaptive Test Assembly for Personalized Measurement of Cognitive Abilities Under Continuous Item Bank Growth. [PDF]

J Intell
Xiong J, Tang C, Liu Q, Li F.
europepmc   +1 more source