Results 61 to 70 of about 19,052,981 (305)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Hierarchical Clustering with Spatial Constraints and Standardized Incidence Ratio in Tuberculosis Data

Mathematics, 2020
In this paper, we propose presenting a solution based on socio-epidemiological variables of tuberculosis, considering a clustering with spatial/geographical constraints; and, determine a value of alpha that increases spatial contiguity without ...
Dalila Camêlo Aguiar, Ramón Gutiérrez Sánchez, Edwirde Luiz Silva Camêlo   +2 more
doaj   +1 more source

Numerical models reveal the suitable habitat area for the stock enhancement and release of marine organism larvae in Liaodong Bay

Frontiers in Marine Science, 2023
Stock enhancement can effectively increase population sustainablility and improve fishery resources, making it crucial to discern the suitable habitats for stock enhancement based on efficiency considerations.
Xiaowei Hu, Wenhao Hou, Zhaojun Sheng, Zhaojun Sheng, Yanbin Xi, Jiaxuan Yu, Jiaxuan Yu, Ruijin Zhang, Ruijin Zhang   +8 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Enhanced Carbon Flux Forecasting via STL Decomposition and Hybrid ARIMA-ES-LSTM Model in Amazon Forest

IEEE Access
This study presents a hybrid model, STL-ARIMA-ES-LSTM, developed to improve the accuracy of Gross Primary Productivity (GPP) forecasts in the Amazon region. The model integrates seasonal and trend decomposition using Loess (STL) with statistical methods (
Jean A. C. Dias, Pedro H. Do V. Guimaraes, Williane G. S. Pereira, Leonardo De O. Tamasauskas, Marivan S. Gomes, Alan B. S. Correa, Karla Figueiredo, Gilson Costa, Gabriel Brito Costa, Fernando A. R. Costa, Marcos C. Da R. Seruffo   +10 more
doaj   +1 more source

Productivity Equation and the m Distributions of Information Processing in Workflows

Applied System Innovation, 2019
This research proposes and investigates an equation for productivity in hybrid workflows regarding its robustness towards the definition of workflows as a hybrid probabilistic systems.
Charles Roberto Telles
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Estimation of state complexity of combined operations

Theoretical Computer Science, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zoltán Ésik, Yuan Gao 0001, Guangwu Liu, Sheng Yu 0001   +3 more
openaire   +4 more sources

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source