Results 151 to 160 of about 6,759,106 (297)

Bayesian Methods for Measuring Operational Risk [PDF]

open access: yes
The likely imposition by regulators of minimum standards for capital to cover 'other risks' has been a driving force behind the recent interest in operational risk management.
Carol Alexander
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Journal of operational oceanography

open access: yes, 2010
The Journal of Operational Oceanography is the only international peer reviewed journal that links the latest research in marine science and technology to its application as part of a sustained system for observing and forecasting our oceans and ...
PINARDI, NADIA
core  

Technique of Operative Cholangiography

open access: yesInternational Journal of Clinical Practice, 1973
openaire   +2 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Operational and real-time Business Intelligence [PDF]

open access: yes
A key component of a company’s IT framework is a business intelligence (BI) system. BI enables business users to report on, analyze and optimize business operations to reduce costs and increase revenues.
Daniela Ioana SANDU
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Development Optimal Site Selection Factors of Hostels

open access: yes, 2015
European Conference on Operational Research國外國際20150712~20150715Y電子版YGlasgow ...
Juan, Pin-Ju; Juan, Peng-Yu, 阮聘茹
core  

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