Results 71 to 80 of about 51,482,631 (285)

Toward Quantum Gate-Model Heuristics for Real-World Planning Problems

open access: yesIEEE Transactions on Quantum Engineering, 2020
Many challenging scheduling, planning, and resource allocation problems come with real-world input data and hard problem constraints, and reduce to optimizing a cost function over a combinatorially defined feasible set, such as colorings of a graph ...
Tobias Stollenwerk   +2 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Military Operations Research Society (MORS) Oral History Project Interview of Dr. Mark T. Lewellyn [PDF]

open access: yes, 2022
Interviewers: Dr. George Akst, FS, and Dr. Bob Sheldon, FS.
Lewellyn, Mark T.   +2 more
core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Military Operations Research Society (MORS) Oral History Project Interview of Dr. Susan M. Sanchez

open access: yes
Interviewers: W. David Kelton, Ms. Tammy McNeley, and Dr. Bob SheldonDr. Susan M. Sanchez is a Distinguished Professor Emerita in the Operations Research (OR) Department at the Naval Postgraduate School (NPS). She joined the OR Department at NPS in 2000.
Sanchez, Susan M.
core   +2 more sources

Military Operations Research Society (MORS) Oral History Project Interview of Mr. Edward A. “Ted” Smyth [PDF]

open access: yes, 2020
Interviewers: Mr. Bill Dunn, FS; Mr. Cortez ‘‘Steve’’ Stephens; and Dr. Bob Sheldon, FS.
Smyth, Edward A. “Ted”
core   +1 more source

Didactic Visualization of Routing Problems

open access: yesEducation Sciences, 2020
The Traveling Salesman and Vehicle Routing Problems are integral parts of bachelor and master programs related to Operations Research/Management Science. This is due to their relevance in both practical applications and research.
Margaretha Gansterer, Veronika Klug
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

SAPEVO-PC: Integrating Multi-Criteria Decision-Making and Machine Learning to Evaluate Navy Ships

open access: yesJournal of Marine Science and Engineering
The selection of a navy ship is essential to guarantee a country’s sovereignty, deterrence capabilities, and national security, especially in the face of possible conflicts and diplomatic instability.
Igor Pinheiro de Araújo Costa   +6 more
doaj   +1 more source

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