Results 211 to 220 of about 733,074 (265)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Transition to robotic adrenalectomy: a surgeon-specific learning curve evaluation. [PDF]

J Robot Surg
Akbulut S, Ozel TM, Celik A, Yildiz G, Deniz E, Sari S.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Outcomes of robotic anatomic lung resection after neoadjuvant therapy for non-small cell lung cancer. [PDF]

Front Surg
Yongue C, Asban A, McCormack A, Snyder CA, Ferraro I, Pachos N, Zervos M, Cerfolio R.   +7 more
europepmc   +1 more source

Irreducible operators.

Michigan Mathematical Journal, 1968
openaire   +3 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Non-operative treatment strategy versus surgery for children with simple appendicitis: non-inferiority randomised controlled trial. [PDF]

BMJ Med
van Amstel P, Bachiri S, Knaapen M, van der Lee JH, van Eekelen R, Bemelman WA, Rippen-Wagner H, Bijlsma TS, Blanken-Peeters CFJM, Boerma EG, van den Boom AL, van den Broek FJC, Cense HA, van Duijvendijk P, Garssen FP, In 't Hof KH, Leijdekkers VJ, Lijkwan MA, Zijp GW, Heij HA, Derikx JPM, van Heurn ELW, Bakx R, Gorter RR, APAC collaborative study group.   +24 more
europepmc   +1 more source

A high rate of falls and traumatic fractures occurs after extensor mechanism reconstruction: a cohort study including both allograft and synthetic mesh grafts. [PDF]

Arthroplasty
Braun S, Selkridge I, Nocon A, Sculco PK.   +3 more
europepmc   +1 more source

Open Reduction and Internal Fixation of a Comminuted Displaced Radial Head Fracture in a 12-Year-Old Female: A Case Report. [PDF]

J Orthop Case Rep
Veetil HHM, Jain A, Gulihar A, Gokaraju K.   +3 more
europepmc   +1 more source

Achieving Safe Zone Cup Positioning in Total Hip Arthroplasty using Anatomical Landmarks: A Prospective Computed Tomography-based Evaluation. [PDF]

J Orthop Case Rep
Bhowmick L, Naskar AK, Gajbhare S, Kunwar S, Pawar SS, Sirsat AD.   +5 more
europepmc   +1 more source