Results 201 to 210 of about 1,120,982 (307)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Transition to robotic adrenalectomy: a surgeon-specific learning curve evaluation. [PDF]

J Robot Surg
Akbulut S, Ozel TM, Celik A, Yildiz G, Deniz E, Sari S.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Robotic single-port (SP) vaginal hysterectomy: the first cases in Europe and surgical steps. [PDF]

Surg Endosc
Otrante L, Moniod L, Rousseau C, Chauleur C.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

TRATAMIENTO QUIRÚRGICO DE ANEURISMAS INTRACRANEALES GIGANTES CON CIRCULACIÓN EXTRACORPÓREA EN EL CARDIOCENTRO / Surgical treatment of giant intracranial aneurysm using cardiopulmonary bypass at the cardiocentro [PDF]

CorSalud, 2011
Armando Alemán Rivera, Alina Ceballos Álvarez, Alain Moré Duarte, Osvaldo González Alfonso, Leonel Fuentes Herrera, Pedro Aníbal Hidalgo Menéndez   +5 more
doaj  

Functional and Clinical Outcomes after Medial Unicompartmental Knee Arthroplasty Compared with High Tibial Osteotomy in Isolated Medial Compartment Osteoarthritis. [PDF]

J Orthop Case Rep
Kyada M, Khare T, Singh SK, Khan AA, Hegde A, Biswas G.   +5 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Evaluation of surgical evacuation of the uterus for abortion and management of miscarriage in patients with sickle cell disease: A multicentre UK study. [PDF]

Br J Haematol
Wolf S, Lewis N, Oyesanya F, Birthwright K, Masters T, Andreeva A.   +5 more
europepmc   +1 more source