Results 91 to 100 of about 15,284,288 (239)

Analysis of the application effect of an automated eye position fixation training device in patients undergoing pterygium surgery: a two-year follow-up randomized controlled trial

Frontiers in Medicine
ObjectiveThis study aimed to evaluate the long-term effects of an automated eye position fixation training device (AEPFTD) on intraoperative cooperation, surgical efficiency, complications, and recurrence rates in patients undergoing pterygium surgery ...
Bei Chen, Bei Chen, Meng Si, Fan Chen, Fei Jiang, Xueqin Chu, Huarong Wu, Rongfeng Liao   +7 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Increased Surgical Duration Associated With Prolonged Hospital Stay After Isolated Posterior Cruciate Ligament Reconstruction

Therapeutics and Clinical Risk Management, 2019
Hasani W Swindell,1 Venkat Boddapati,1 Julian J Sonnenfeld,1 David P Trofa,1 James E Fleischli,2 Christopher S Ahmad,1 Charles A Popkin1 1Department of Orthopedic Surgery, Columbia University Medical Center, New York, NY, USA; 2Shoulder and Elbow Center,
Swindell HW, Boddapati V, Sonnenfeld JJ, Trofa DP, Fleischli JE, Ahmad CS, Popkin CA   +6 more
doaj  

Extraperitoneal single-port robot-assisted radical prostatectomy using da Vinci Xi platform: learning curve and outcome analysis

Asian Journal of Andrology
This single-center retrospective cohort study evaluated the feasibility, safety, and learning curve of extraperitoneal single-port robot-assisted radical prostatectomy using the da Vinci Xi platform for localized prostate cancer.
Li-Chen Chen, Yan Wang, Xing-Lin Chen, Ming-Yue Tan, Guan-Qun Ju, Dong-Liang Xu   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Warm aortic arch repair: Redefining proximal aortic arch surgeryCentral MessagePerspective

JTCVS Techniques
Background: We recently introduced warm aortic arch repair, a new novel approach that obviates the need for hypothermic circulatory arrest. However, there have been no comparative analyses with conventional repair.
Shinichi Fukuhara, MD, Robert B. Hawkins, MD, MSc, Gorav Ailawadi, MD, Barbara Hamilton, MD   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

CHARACTERISTICS OF PLEURAL ADHESIONS, OPERATIVE TIME, AND BLOOD LOSS IN PATIENTS OPERATED ON FOR PULMONARY TUBERCULOSIS

Паёми Сино
Objective: To evaluate the incidence and severity of pleural adhesions, blood loss volume, and operative time in patients with pulmonary tuberculosis (PTB).
Aliev Vilayat Kamalovich, Sadovnikova Svetlana Sergeevna, Mishin Igor Sergeevich, Bagirov Mamed Adilovich,   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source