Results 141 to 150 of about 15,284,288 (239)

Association between umbilicus-symphysis pubis distance and operative time in transabdominal preperitoneal (TAPP) inguinal hernia repair. [PDF]

Hernia
Gülçek E, Aydoğdu YF, Özaydın S, Büyükkasap Ç.   +3 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Perioperative Predictors of Complications and Flap Loss in Microvascular Reconstructive Surgery: The Role of Fluid Balance, Crystalloid Administration and Operative Time. [PDF]

J Clin Med
Torabi S, Omuro PK, Overbeek R, Adam EH, Stoll SE, Kammerer T, Schroeder C, Zirk M, Steinbicker AU, Dusse F, Zinser M.   +10 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Does supine versus lateral position affect operative time and reduction quality for elderly intertrochanteric femur fractures? [PDF]

Eur J Orthop Surg Traumatol
Ross RC, Shabani S, Sakka B, Figueras J, Allen M, Lee J, Zalavras C, Shepherd L, Patterson JT, Gary JL.   +9 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Report of Operative #457

, 1914
Physical condition: GoodIn this report, an operative working in the Mill reports on the actions and attitudes of other mill workers towards the ...
Operative #457
core  

Predicting operative time in robotic ventral hernia repair using machine learning: a retrospective pilot study. [PDF]

Langenbecks Arch Surg
Brucchi F, Gori A, Van Campenhout I, Colpaert J, Boterbergh K, Potvlieghe P, Violante T, Rottoli M, Dionigi G, Muysoms F, Bossche BVD.   +10 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source