Results 61 to 70 of about 15,284,288 (239)

Radical prostatectomy assisted by the Da Vinci robotic system in patients with prostate cancer at the Instituto Nacional de Enfermedades Neoplásicas

Anales de la Facultad de Medicina
Introduction. Pancreatic cancer has an unfavorable prognosis. Surgery is the only potentially curative treatment, but complications affect approximately 40% of patients, hindering recovery and long-term outcomes. Objective.
Víctor Alberto Destefano-Urrutia, Nepton Víctor David Ruiz-Aguilar, Gustavo Hipólito Diaz-Infantes, Edgar Fermín Yan-Quiroz, José Richard Tenazoa-Villalobos   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Minimally Invasive Percutaneous Nephrolithotomy for Staghorn Calculus – A Single-Center Study

Journal of Nobel Medical College
Background: Staghorn calculi, either partial or complete, present a significant urological challenge. Mini-percutaneous nephrolithotomy (mPCNL) has become a less invasive alternative to standard PCNL (sPCNL).
Ram Sagar Shah, Kartikesh Mishra, Sachidanand Sah, Abhishek Poudel   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Report of Operative #316

, 1920
Physical condition: GoodIn this report, an operative describes the activities of mill workers and working conditions in the ...
Operative #316
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Pacific co-operator.

, 1913
Published by, : Pacific Co-operative League.Published by, Aug. 1913- : Co-operative Publishing Company.Official organ for the Farmers' Co-operative Educational Union of America, California Division, and the Rochdale Co-operative Societies of California ...
Rochdale Co-operative Societies of California., Pacific Co-operative League.   +1 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The learning curve of novel implant total knee arthroplasty system in high-volume university center

SICOT-J
Introduction: The learning curve associated with adopting new surgical systems in total knee arthroplasty (TKA) can significantly impact surgical efficiency and patient outcomes. This study aimed to evaluate the evolution of operative time with the KNEO®
Messe Simon, Mesnard Guillaume, Vermue Hannes, Festa Enrico, Servien Elvire, Viste Anthony, Batailler Cécile, Lustig Sébastien   +7 more
doaj   +1 more source