Results 171 to 180 of about 2,866,909 (331)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

<i>N</i> =1 Super Virasoro Tensor Categories. [PDF]

Commun Math Phys
Creutzig T, McRae R, Orosz Hunziker F, Yang J.   +3 more
europepmc   +1 more source

Ribbon Operators and Hall-Littlewood Symmetric Functions [PDF]

, 2000
Mike Zabrocki
openalex   +1 more source

Irreducible operators.

Michigan Mathematical Journal, 1968
openaire   +3 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Variability analysis of a low-cost paper dipstick nucleic acid extraction method for wastewater surveillance using gage repeatability and reproducibility. [PDF]

Sci Rep
Ahuja S, Kulkarni A, Kondabagil K, Tallur S.   +3 more
europepmc   +1 more source

Bivariate Shepard-Bernoulli operators [PDF]

, 2014
Francesco Dell’Accio, Filomena Di Tommaso   +1 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Analysis of Risk Factors for Postoperative Delayed Perforation Following Endoscopic Submucosal Dissection of Gastrointestinal Stromal Tumors. [PDF]

Surg Laparosc Endosc Percutan Tech
Guo C, Xue L, Pan G, Chen S, Wu X, Li S.
europepmc   +1 more source

Boundary Data Maps for Schrodinger Operators on a Compact Interval [PDF]

, 2010
Stephen Clark, Fritz Gesztesy, Marius Mitrea   +2 more
openalex   +1 more source