Results 11 to 20 of about 61,017 (237)
Non-operative management of rectal cancer: understanding tumor biology [PDF]
Minerva Chirurgica, 2018 The management of locally-advanced rectal cancer involves a combination of chemotherapy, chemoradiation, and surgical resection to provide excellent local tumor control and overall survival. However, aspects of this multimodality approach are associated with significant morbidity and long-term sequelae.
Iris H Wei, Julio Garcia-Aguilar
openaire +3 more sources
Recent Advances in Operations Research in Computational Biology, Bioinformatics and Medicine [PDF]
RAIRO - Operations Research, 2016 The EURO Working Group on Operations Research in Computational Biology, Bioinformatics and Medicine held its fourth conference in Poznan-Biedrusko, Poland, June 26–28, 2014. The editorial board of RAIRO-OR invited submissions of papers to a special issue on Recent Advances in Operations Research in Computational Biology, Bioinformatics and Medicine ...
Metin Turkay +3 more
openaire +4 more sources
The Convergence of Behavioral Biology and Operant Psychology: Toward an Interlevel and Interfield Science [PDF]
The Behavior Analyst, 1989 Behavioral biology and operant psychology have developed in parallel but separate paths since their origins in the 1930s. In the first three decades, both fields dealt with microscopic (or molecular) controlling variables and qualitative data. Since about 1960, both have primarily focused on macroscopic (or molar) controlling variables.
John K. Robinson, William R. Woodward
openaire +3 more sources
Moving in the Dark: Enlightening the Spatial Population Ecology of European Cave Salamanders
Population Ecology, EarlyView.We assessed individual interactions, movement ecology and activity patterns of a subterranean population of Speleomantes strinatii, applying spatial capture–recapture modeling to a photographic dataset of 104 individuals. ABSTRACT Space use and movement are fundamental aspects of organisms' ecology, mirroring individual fitness, behavior, and life ...
Giacomo Rosa +2 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Concrete and Formal Operational Thought: Implications for Introductory College Biology [PDF]
The American Biology Teacher, 1976 THE COGNITIVE ABILITIES of concrete operational and formal operational thinkers, as defined by the Swiss psychologist Jean Piaget, have received a great deal of attention in recent years. This article briefly describes the stages involved in Piaget's model and reviews the current literature as it applies to Piaget's ideas and specifically to students ...
Ronald G. Good, Suzanne B. Haley
openaire +2 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source