Results 81 to 90 of about 1,317,588 (284)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

On Kantorovich modification of ( p , q ) $( p,q ) $ -Baskakov operators

Journal of Inequalities and Applications, 2016
The concern of this paper is to introduce a Kantorovich modification of ( p , q ) $( p,q ) $ -Baskakov operators and investigate their approximation behaviors. We first define a new ( p , q ) $( p,q ) $ -integral and construct the operators.
Tuncer Acar, Ali Aral, Syed Abdul Mohiuddine   +2 more
doaj   +1 more source

c=1 Liouville Theory Perturbed by the Black-Hole Mass operator

, 1993
We discuss the properties of the Liouville theory coupled to the c=1 matter when perturbed by an operator, the screening operator of the $SL(2;R)$ current algebra, which is supposed to generate the mass of the two-dimensional black hole.
Barbon, Bars, Bershadsky, Bouwknegt, Chandrasekhar, Chaudhuri, Danielsson, Das, David, Demeterfi, Dhar, Dijkgraaf, Distler, Dotsenko, Eguchi, Elizur, Gross, Jevicki, Kachru, Kitazawa, Klebanov, Knizhnik, Kostov, Lian, Mandal, Marcus, Martinec, Rama, Sakai, Tohru Eguchi, Witten, Witten   +31 more
core   +1 more source

On the Homology Theory of Operator Algebras [PDF]

International Journal of Mathematics and Mathematical Sciences, 2012
We investigate the cyclic homology and free resolution effect of a commutative unital Banach algebra. Using the free resolution operator, we define the relative cyclic homology of commutative Banach algebras. Lemmas and theorems of this investigation are studied and proved.
openaire   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Generalized ( p , q ) $(p,q)$ -Bleimann-Butzer-Hahn operators and some approximation results

Journal of Inequalities and Applications, 2017
The aim of this paper is to introduce a new generalization of Bleimann-Butzer-Hahn operators by using ( p , q ) $(p,q)$ -integers which is based on a continuously differentiable function μ on [ 0 , ∞ ) = R + $[0,\infty)=\mathbb{R}_{+}$ . We establish the
M Mursaleen, Md Nasiruzzaman, Khursheed J Ansari, Abdullah Alotaibi   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Approximation by Schurer Type λ-Bernstein–Bézier Basis Function Enhanced by Shifted Knots Properties

Mathematics
In this article, a novel Schurer form of λ-Bernstein operators augmented by Bézier basis functions is presented by utilizing the features of shifted knots.
Abdullah Alotaibi
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source