Results 171 to 180 of about 736,346 (302)

Performance of Transvaginal First-Trimester Anatomical Screening by Operators with Different Levels of Experience: A Randomized Controlled Trial. [PDF]

Diagnostics (Basel)
Leesukon P, Dulyaphat W, Moradokkasem W, Lertrat W, Diawtipsukon S, Chansriniyom N, Tongsong T, Tangshewinsirikul C.   +7 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Standardizing Vegetation Size Measurement in Native Left-Sided Infective Endocarditis Using Artificial Intelligence. [PDF]

J Clin Med
Pinilla-García D, Cabezón-Villalba G, Llamas-Fernández L, González-Juanatey C, López-Azor JC, Olmos C, Pidone C, Anguita-Sánchez M, Martínez-Dolz L, Gómez-Salvador I, López-Pena AM, Ramos-López N, Gómez-Ramírez D, Delgado V, Castillo-Domínguez JC, Ladrón R, Gil JF, de Miguel M, Sevilla T, Revilla-Orodea A, López J, San Román JA, Baladrón C.   +22 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Near-Frustration-Free Electronic Structure Hamiltonian Representations and Lower-Bound Certificates. [PDF]

J Chem Theory Comput
Rubin NC, Low GH, DePrince Iii AE.
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Regulatory oversight of indoor air quality in ice arenas is needed in Canada. [PDF]

CMAJ
Vecchiarelli V.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Enhancing blood transfusion safety through RFID-based verification and human factors engineering. [PDF]

Front Med Technol
Angelucci A, Zummo F, Giudici R, Fumagalli R, Aliverti A, Bassi G.   +5 more
europepmc   +1 more source