Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Adoption of intravascular imaging use among intermediate to high-volume operators in the United States from 2019 to 2023: a Medicare data analysis. [PDF]
J Invasive CardiolMurugiah K +6 more
europepmc +1 more source
Aging and Cancer, EarlyView.In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source
Regulatory Whack-a-mole: A Rapid Scoping Review of Gambling Marketing Restrictions and their (in)Effectiveness. [PDF]
Curr Addict RepTorrance J +7 more
europepmc +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
HCQ-SGuA: A Plant-Growth-Inspired Hybrid Saplings Growing Up Algorithm with Quasi-Random Initialization and Chaotic Operator Control for Continuous Optimization. [PDF]
Biomimetics (Basel)Seyyarer E.
europepmc +1 more source
Ethical Foreground and Background in Adult Educator Work
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
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A Dual-Modal Hybrid Marker for Automatic Registration and Coordinate Hand-Over in C-Arm CT-Guided Spinal Navigation. [PDF]
Sensors (Basel)Kim T, Kim S.
europepmc +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Anatomical Risk Factors for Technical Failure of the Perclose Vascular Closure Device: A Single-Center Retrospective Study. [PDF]
Ann Vasc DisJinno H +9 more
europepmc +1 more source