Results 51 to 60 of about 761,097 (307)

Pseudodifferential Operators Associated with a Semigroup of Operators [PDF]

open access: yesJournal of Fourier Analysis and Applications, 2013
20 ...
Bernicot, Frédéric, Frey, Dorothee
openaire   +5 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Thirty-fourth Illinois Custom Spray Operators Training School: summaries of presentations [PDF]

open access: yes, 1982
Made available in DSpace on 2016-03-17T21:24:51Z (GMT). No. of bitstreams: 2 749322_1982.pdf: 36642161 bytes, checksum: e5c67aa8fc31681400d7f6a31d20ba53 (MD5) license.txt: 4846 bytes, checksum: 927d59ba442de31571446841df3d90ca (MD5) Previous issue date:
Illinois Custom Spray Operators' School
core  

Power vector inequalities for operator pairs in Hilbert spaces and their applications

open access: yesOpen Mathematics
This study explores the power vector inequalities for a pair of operators (B,C)\left(B,C) in a Hilbert space. By utilizing a Mitrinović-Pečarić-Fink-type inequality for inner products and norms, we derive various power vector inequalities.
Altwaijry Najla   +2 more
doaj   +1 more source

The binary algorithm of cascade connection of nonlinear digital filters described in functional series [PDF]

open access: yesBulletin of the Polish Academy of Sciences: Technical Sciences, 2019
The article presents an example of the use of functional series for the analysis of nonlinear systems for discrete time signals. The homogeneous operator is defined and it is decomposed into three component operators: the multiplying operator, the ...
M. Siwczyński, S. Żaba
doaj   +1 more source

Singular integral operators, a brief historical overview of its evolution

open access: yesSelecciones Matemáticas, 2022
In this work we give an analytical-historical view of the classical theory of singular integrals introduced by A.P. Calderón-A. Zygmund. Emphasis is given to their applications to PDEs and to some projections of the theory.
Alejandro Ortiz Fernández
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy