Results 211 to 220 of about 114,910 (254)
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The Structure of the mer Operon
1985The DNA sequence has been determined for a 3.8-kb region which encodes the mercury-resistance (mer) operon of the IncFII plasmid NR1. The sequence reveals 4 open reading frames which could encode proteins of 12,522, 9,429, 14,965, and 58,912 d corresponding to the 4 previously described Hg-inducible proteins detected in minicells carrying mer+ plasmids.
P, Barrineau +5 more
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The Post-transcriptional Operon
2010A post-transcriptional operon is a set of monocistronic mRNAs encoding functionally related proteins that are co-regulated by a group of RNA-binding proteins and/or small non-coding RNAs so that protein expression is coordinated at the post-transcriptional level. The post-transcriptional operon model (PTO) is used to describe data from an assortment of
Tenenbaum, Scott A. +2 more
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Regulation of the lactose operon in vitro
Molecular and General Genetics MGG, 1970Using DNA of phage ϕ80p lac carrying lac-operon (i+o+z+y+), the transcription of the lac-operon was studied in vitro. The lac-specific mRNA having a molecular size of 28S was detected by hybridizing messenger RNA (mRNA) from induced cells (diploid for the lac-operon) to the ϕ80p lac DNA. The hybridization of lac-specific mRNA to ϕ80p lac DNA was almost
Y, Iida +3 more
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Operon prediction by Markov clustering
International Journal of Data Mining and Bioinformatics, 2014The prediction of operons is a critical step for the reconstruction of biochemical and regulatory networks at the whole genome level. In this paper, a novel operon prediction model is proposed based on Markov Clustering (MCL). The model employs a graph-clustering method by MCL for prediction and does not need a classifier.
W. Du +5 more
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microRNAs and the Operon Paper
Journal of Molecular Biology, 2011The "Operon paper" by F. Jacob and J. Monod started 50 years of research into understanding how the expression of genes is regulated on a molecular level. Ten years ago, microRNAs (miRNAs) emerged as major regulators of eukaryotic gene expression. Here, I will review the basic principles of gene regulation by miRNAs and how these principles can be ...
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Journal of Molecular Biology, 2013
The ability to regulate gene expression is essential for controlling metabolic events in a cell. Proteins that function like molecular switches respond to fluctuations in the environment to maintain homeostasis. The operon model, proposed by Jacob and Monod, provides a cogent depiction for how gene expression is regulated. A molecular mechanism for the
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The ability to regulate gene expression is essential for controlling metabolic events in a cell. Proteins that function like molecular switches respond to fluctuations in the environment to maintain homeostasis. The operon model, proposed by Jacob and Monod, provides a cogent depiction for how gene expression is regulated. A molecular mechanism for the
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Improved BioCyc Operon Prediction: Revisiting the Operon Prediction Problem
Abstract Introduction Operon prediction is a valuable component of microbial-genome annotation because operon organization can yield inferences about gene function, and because knowledge of operon structure can aid the interpretation of gene expression data.Peter E. Midford +2 more
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Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond
Annual Review of Biochemistry, 2021Max A English +2 more
exaly
COMPUTATIONAL ELUCIDATION OF OPERONS AND UBER-OPERONS
2008PHUONGAN DAM +6 more
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