The life-cycle of operons. [PDF]
PLoS Genetics, 2006 Operons are a major feature of all prokaryotic genomes, but how and why operon structures vary is not well understood. To elucidate the life-cycle of operons, we compared gene order between Escherichia coli K12 and its relatives and identified the ...
Morgan N Price, Adam P Arkin, Eric J Alm
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Data Mining of Groundwater Genomes for Metagenome-Assembled Genomes (MAGs) Containing Monooxygenase Operons Associated with Contaminant Biodegradation [PDF]
BiologyThis study examined freely available whole genome sequencing (WGS) data for genes associated with contaminant biodegradation. Thirteen WGS datasets (>600 individual samples) involving more than 12,000 Gbases from multiple countries were examined.
Alison M. Cupples +2 more
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Operon Prediction Model Based on Markov Clustering Algorithm [PDF]
International Journal Bioautomation, 2019 There are many operon prediction models, but few methods can be applied to the operon prediction of new sequencing species effectively. In this paper, an operon prediction model based on Markov clustering algorithm is proposed.
Zhenmei Zhang, Yongquan Liang
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A transcription unit based systems biology study on Salmonella typhimurium gene organization, evolution, co-expression, and regulation [PDF]
Frontiers in MicrobiologyA bacterial transcription unit (TU) could be composed of a single gene or multiple adjacent genes forming an operon. Traditional systems biology often relies on gene-centric analysis, overlooking the regulatory complexity inherent in the operon structure,
Leting Sun +9 more
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Validation of a model of regulation in the tryptophan operon against multiple experiment data using global optimisation [PDF]
, 2009 This paper is concerned with validating a mathematical model of regulation in the tryptophan operon using global optimization. Although a number of models for this biochemical network are proposed, in many cases only qualitative agreement between the ...
Kim, Jung-Su +9 more
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eLife, 2021 Prokaryotes utilize polycistronic messages (operons) to co-translate proteins involved in the same biological processes. Whether eukaryotes achieve similar regulation by selectively assembling and translating monocistronic messages derived from different
Rohini R Nair +7 more
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Reporter Gene-Based qRT-PCR Assay for Rho-Dependent Termination In Vivo
Cells, 2023 In bacteria, the Rho protein mediates Rho-dependent termination (RDT) by identifying a non-specific cytosine-rich Rho utilization site on the newly synthesized RNA. As a result of RDT, downstream RNA transcription is reduced.
Monford Paul Abishek N +3 more
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Stoichiometry of the Gene Products From the Tetrachloroethene Reductive Dehalogenase Operon pceABCT
Frontiers in Microbiology, 2022 Organohalide respiration (OHR) is a bacterial anaerobic process that uses halogenated compounds, e.g., tetrachloroethene (PCE), as terminal electron acceptors.
Lorenzo Cimmino +3 more
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Diel gene expression improves software prediction of cyanobacterial operons [PDF]
PeerJ, 2022 Cyanobacteria are important participants in global biogeochemical process, but their metabolic processes and genomic functions are incompletely understood.
Philip Heller
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Cellular and Molecular Life Sciences, 2009 Operons (clusters of co-regulated genes with related functions) are common features of bacterial genomes. More recently, functional gene clustering has been reported in eukaryotes, from yeasts to filamentous fungi, plants, and animals. Gene clusters can consist of paralogous genes that have most likely arisen by gene duplication. However, there are now
Osbourn, Anne E., Field, Ben
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