Results 71 to 80 of about 118,072 (257)

Characterization of carABpyrB operon and role of pyrE in Francisella novicida biofilm. [PDF]

Microbiologyopen
Pyrimidine biosynthesis links metabolism to biofilm regulation in Francisella novicida. During nutrient limitation, reduced pyrimidine availability shifts metabolism from uracil salvage to de novo synthesis, increasing biofilm formation. Mutants in carABpyrB exhibit uracil‐dependent growth defects and elevated biofilm:growth ratios, revealing ...
Sprinkel KC, Geiger AR, van Hoek ML.
europepmc   +2 more sources

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

Advanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu, Yufan Xie, Lanxin Wang, Luyan Ma, Xiaofei Ge, Jiawei Wang   +5 more
wiley   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Synthetic Shewanella‐Bacillus Microbial Consortia for Enhanced Metal Oxide Leaching From Spent Lithium‐Ion Batteries Using Brewing Wastewater as Leaching Agent

Advanced Science, EarlyView.
A recycling approach of spent lithium‐ion batteries is developed using brewing wastewater as the leaching agent and an engineering microbial consortium as the biocatalyst. Shewanella oneidensis reduces spent LiNixCoyMn1‐x‐yO2 cathodes via extracellular electron transfer, while Bacillus subtilis removes residual ethanol to eliminate inhibition.
Baocai Zhang, Chunxiao Qiao, Huichun Liu, Yiyun Wang, Yan Liu, Huan Yu, Junqi Zhang, Chao Li, Deguang Wu, Qulai Tang, Zhiwen Wang, Danni Zhang, Dake Xu, Feng Li, Hao Song   +14 more
wiley   +1 more source

stg fimbrial operon from S. Typhi STH2370 contributes to association and cell disruption of epithelial and macrophage-like cells

Biological Research, 2015
BACKGROUND: Salmonella enterica serovar Typhi (S. Typhi) stg operon, encoding a chaperone/usher fimbria (CU), contributes to an increased adherence to human epithelial cells.
Liliana Berrocal, Juan A Fuentes, A Nicole Trombert, Matías R Jofré, Nicolás A Villagra, Luis M Valenzuela, Guido C Mora   +6 more
doaj   +1 more source

Conjugated Polymer‐Microbe Interactions Trigger Regulatory Reprogramming for Enhanced Bioelectrocatalysis

Advanced Science, EarlyView.
Conjugated polymer‐supported bioelectrochemical systems are shown to enhance microbial electrosynthesis by triggering coordinated electrochemical, transcriptional, post‐transcriptional (sRNA), metabolic, and protein‐level responses. Integrated multi‐omics and electrochemical analyses reveal selective physiological remodeling associated with improved ...
David Ohayon, Yuanmei Liang, Zexuan Wang, Jee Loon Foo, Glenn Quek, Samantha R. McCuskey, Zhongxin Chen, Matthew Wook Chang, Guillermo C. Bazan   +8 more
wiley   +1 more source

Characterization of relationships between transcriptional units and operon structures in Bacillus subtilis and Escherichia coli

BMC Genomics, 2007
Background Operon structures play an important role in transcriptional regulation in prokaryotes. However, there have been fewer studies on complicated operon structures in which the transcriptional units vary with changing environmental conditions ...
Kanehisa Minoru, Ogasawara Naotake, Kobayashi Kazuo, Kawashima Shuichi, Okuda Shujiro, Goto Susumu   +5 more
doaj   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

Advanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim, Jiwon Lee, Minjeong Kang, Sung Sun Yim, Donghui Choe, Byung‐Kwan Cho   +5 more
wiley   +1 more source

LurR is a regulator of the central lactate oxidation pathway in sulfate-reducing Desulfovibrio species.

PLoS ONE, 2019
The central carbon/lactate utilization pathway in the model sulfate-reducing bacterium, Desulfovibrio vulgaris Hildenborough, is encoded by the highly conserved operon DVU3025-3033.
Lara Rajeev, Eric G Luning, Grant M Zane, Thomas R Juba, Alexey E Kazakov, Pavel S Novichkov, Judy D Wall, Aindrila Mukhopadhyay   +7 more
doaj   +1 more source

Isoprenoid Pyrophosphate-Dependent Transcriptional Regulation of Carotenogenesis in Corynebacterium glutamicum

Frontiers in Microbiology, 2017
Corynebacterium glutamicum is a natural producer of the C50 carotenoid decaprenoxanthin. The crtEcg0722crtBIYEb operon comprises most of its genes for terpenoid biosynthesis.
Petra Peters-Wendisch, Nadja A. Henke, Sabine A. E. Heider, Silvin Hannibal, Volker F. Wendisch   +4 more
doaj   +1 more source