Results 11 to 20 of about 114,748 (203)

A transcription unit based systems biology study on Salmonella typhimurium gene organization, evolution, co-expression, and regulation [PDF]

Frontiers in Microbiology
A bacterial transcription unit (TU) could be composed of a single gene or multiple adjacent genes forming an operon. Traditional systems biology often relies on gene-centric analysis, overlooking the regulatory complexity inherent in the operon structure,
Leting Sun, Zhixuan Deng, Junya Zhang, Xin Cao, Shuhong Liu, Runhong Chen, Min Zheng, Yejun Wang, Yejun Wang, Yejun Wang   +9 more
doaj   +2 more sources

Identification of the Integration/Excision Module and Regulatory Elements Involved in the Mobility of IME8, an Integrative and Mobilizable Element From Mosquitocidal Lysinibacillus sphaericus [PDF]

Microbial Biotechnology
Lysinibacillus sphaericus, a bacterium successfully used in the control of mosquitoes, bears its insecticidal traits in GI8, a recently identified mosquitocidal genomic island.
Yifeng Hu, Ying Yang, Xiaomin Hu, Jacques Mahillon, Zubin Chen, Han Xia   +5 more
doaj   +2 more sources

Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology

eLife, 2021
Prokaryotes utilize polycistronic messages (operons) to co-translate proteins involved in the same biological processes. Whether eukaryotes achieve similar regulation by selectively assembling and translating monocistronic messages derived from different
Rohini R Nair, Dmitry Zabezhinsky, Rita Gelin-Licht, Brian J Haas, Michael CA Dyhr, Hannah S Sperber, Chad Nusbaum, Jeffrey E Gerst   +7 more
doaj   +1 more source

Reporter Gene-Based qRT-PCR Assay for Rho-Dependent Termination In Vivo

Cells, 2023
In bacteria, the Rho protein mediates Rho-dependent termination (RDT) by identifying a non-specific cytosine-rich Rho utilization site on the newly synthesized RNA. As a result of RDT, downstream RNA transcription is reduced.
Monford Paul Abishek N, Heungjin Jeon, Xun Wang, Heon M. Lim   +3 more
doaj   +1 more source

Stoichiometry of the Gene Products From the Tetrachloroethene Reductive Dehalogenase Operon pceABCT

Frontiers in Microbiology, 2022
Organohalide respiration (OHR) is a bacterial anaerobic process that uses halogenated compounds, e.g., tetrachloroethene (PCE), as terminal electron acceptors.
Lorenzo Cimmino, Adrien W. Schmid, Christof Holliger, Julien Maillard   +3 more
doaj   +1 more source

Diel gene expression improves software prediction of cyanobacterial operons [PDF]

PeerJ, 2022
Cyanobacteria are important participants in global biogeochemical process, but their metabolic processes and genomic functions are incompletely understood.
Philip Heller
doaj   +2 more sources

Internal Promoters and Their Effects on the Transcription of Operon Genes for Epothilone Production in Myxococcus xanthus

Frontiers in Bioengineering and Biotechnology, 2021
The biosynthetic genes for secondary metabolites are often clustered into giant operons with no transcription terminator before the end. The long transcripts are frangible and the transcription efficiency declines along with the process.
Ye Wang, Xin-jing Yue, Shu-fei Yuan, Yu Hong, Wei-feng Hu, Yue-zhong Li   +5 more
doaj   +1 more source

Divide and conquer: genetics, mechanism, and evolution of the ferrous iron transporter Feo in Helicobacter pylori

Frontiers in Microbiology, 2023
IntroductionFeo is the most widespread and conserved system for ferrous iron uptake in bacteria, and it is important for virulence in several gastrointestinal pathogens. However, its mechanism remains poorly understood.
Camilo Gómez-Garzón, Shelley M. Payne, Shelley M. Payne   +2 more
doaj   +1 more source

FADU: a Quantification Tool for Prokaryotic Transcriptomic Analyses

mSystems, 2021
Quantification tools for RNA sequencing (RNA-Seq) analyses are often designed and tested using human transcriptomics data sets, in which full-length transcript sequences are well annotated.
Matthew Chung, Ricky S. Adkins, John S. A. Mattick, Katie R. Bradwell, Amol C. Shetty, Lisa Sadzewicz, Luke J. Tallon, Claire M. Fraser, David A. Rasko, Anup Mahurkar, Julie C. Dunning Hotopp   +10 more
doaj   +1 more source

The Exploration of Novel Regulatory Relationships Drives Haloarchaeal Operon-Like Structural Dynamics over Short Evolutionary Distances

Microorganisms, 2020
Operons are a dominant feature of bacterial and archaeal genome organization. Numerous investigations have related aspects of operon structure to operon function, making operons exemplars for studies aimed at deciphering Nature’s design principles for ...
Phillip Seitzer, Andrew I. Yao, Ariana Cisneros, Marc T. Facciotti   +3 more
doaj   +1 more source