Vulnerabilities in Yersinia pestis caf operon are unveiled by a Salmonella vector. [PDF]
PLoS ONE, 2012 During infection, Yersinia pestis uses its F1 capsule to enhance survival and cause virulence to mammalian host. Since F1 is produced in large quantities and secreted into the host tissues, it also serves as a major immune target.
Ling Cao +5 more
doaj +1 more source
Operon-SEQer ensemble tested against new data sets.
, 2022 Recall (blue) and specificity (red) of the Operon-SEQer ensemble with algorithm agreement cutoffs of 1–6 for operon pair calls for the new data set from (A) B. subtilis, (B) P. syringiae, and (C) M. tuberculosis. (TIF)
Raga Krishnakumar (11909990) +1 more
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, 2022 (A) AUC scores of OperonSEQer operon pair calls on MicrobesOnline E.coli operons, and both OperonSEQer and MicrobesOnline operon pair calls on SMRT-seq E.coli operons.
Raga Krishnakumar (11909990) +1 more
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Operon-SEQer features and performance across the various algorithms used.
, 2022 (A) Spearman’s correlation coefficients between the features considered for use in machine learning and operon pair calls made by MicrobesOnline across 7-species (see main text). KW = Kruskal Wallis statistic.
Raga Krishnakumar (11909990) +1 more
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Gene Gangs of the Chloroviruses: Conserved Clusters of Collinear Monocistronic Genes
Viruses, 2018 Chloroviruses (family Phycodnaviridae) are dsDNA viruses found throughout the world’s inland waters. The open reading frames in the genomes of 41 sequenced chloroviruses (330 ± 40 kbp each) representing three virus types were analyzed for evidence of ...
Phillip Seitzer +5 more
doaj +1 more source
A Microorganism Transcriptional Regulation Algorithm Based on Generalized Regression Neural Network [PDF]
International Journal Bioautomation, 2019 Considering the importance of operon in microorganism transcriptional regulation, this paper sets up a new operon prediction model based on artificial neural network (ANN). Specifically, multiple genome information, ranging from intergenic distance (IGD),
Hui Li
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Copper Chaperone CupA and Zinc Control CopY Regulation of the Pneumococcal
mSphere, 2017 Any metal in excess can be toxic; therefore, metal homeostasis is critical to bacterial survival. Bacteria have developed specialized metal import and export systems for this purpose.
Miranda J. Neubert +3 more
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The role of the Staphylococcal VraTSR regulatory system on vancomycin resistance and vanA operon expression in vancomycin-resistant Staphylococcus aureus. [PDF]
PLoS ONE, 2014 Vancomycin is often the preferred treatment for invasive methicillin-resistant Staphylococcus aureus (MRSA) infection. With the increase in incidence of MRSA infections, the use of vancomycin has increased and, as feared, isolates of vancomycin-resistant
Nadia K Qureshi +2 more
doaj +1 more source
Characterization of carABpyrB operon and role of pyrE in Francisella novicida biofilm. [PDF]
MicrobiologyopenPyrimidine biosynthesis links metabolism to biofilm regulation in Francisella novicida. During nutrient limitation, reduced pyrimidine availability shifts metabolism from uracil salvage to de novo synthesis, increasing biofilm formation. Mutants in carABpyrB exhibit uracil‐dependent growth defects and elevated biofilm:growth ratios, revealing ...
Sprinkel KC, Geiger AR, van Hoek ML.
europepmc +2 more sources
Characterization of the biotin uptake system encoded by the biotin-inducible bioYMN operon of Corynebacterium glutamicum [PDF]
, 2012 Schneider J, Peters-Wendisch P, Stansen KC, et al. Characterization of the biotin uptake system encoded by the biotin-inducible bioYMN operon of Corynebacterium glutamicum. BMC Microbiology.
Götker Susanne +20 more
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