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Ophthalmic Drug Delivery: Development and Regulatory Considerations
Clinical Pharmacology & Therapeutics, 2009This review presents an update on the development of ophthalmic drug delivery systems (Table 1), as well as regulatory aspects of product development. This review is based on full papers and published patents as of November 2008.
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Drug Delivery from Ophthalmic Lenses
2020Glaucoma is one of the most common diseases that is characterized by an increase of the IOP that can lead to the damage of the optical nerve. Glaucoma patients are usually treated with eye drops. However, the effectiveness of glaucoma drops is very law because less than 5% of the applied drug reaches the target. In this paper, we discuss mathematically
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DRUG DELIVERY STRATEGIES FOR COMBINATION OPHTHALMIC TREATMENTS
Retina, 2009The most significant obstacle to the combination of drug therapies in age-related macular degeneration (AMD) may be drug delivery. Although the posterior of the eye can be reached by intravitreal injections and implants, AMD is a chronic disease process that is likely to require prolonged or indefinite exposure to antiproliferative agents.
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The ophthalmic rod: A new ophthalmic drug delivery system I
Graefe's Archive for Clinical and Experimental Ophthalmology, 1990The ophthalmic rod (OR) is a new drug delivery system, intended as an alternative to conventional therapy in ophthalmology. The rod is made of a nontoxic plastic. It is dipped into a drug solution which after drying forms a thin homogeneous coating. The OR is then packed and sterilized by gamma radiation. The effects of radiation on the contents of the
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
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Treatment of muscle‐invasive and advanced bladder cancer in 2020
Ca-A Cancer Journal for Clinicians, 2020Vaibhav G Patel +2 more
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