Animal Models and Experimental Medicine, EarlyView.We developed an animal model of early diabetic retinopathy (DR) in the tree shrew by feeding a high‐fat and high‐sugar diet in combination with STZ. Physiological and biochemical index detection, hematoxylin and eosin staining, and transmission electron microscopy were performed to examine DR.
Min Qiu +10 more
wiley +1 more source
Treatment of allergic conjunctivitis with olopatadine hydrochloride eye drops
Clinical Ophthalmology, 2008 Eiichi UchioDepartment of Ophthalmology, Fukuoka University School of Medicine, Fukuoka, JapanAbstract: Olopatadine hydrochloride exerts a wide range of pharmacological actions such as histamine H1 receptor antagonist action, chemical mediator ...
Eiichi Uchio
doaj
Do Ophthalmic Solutions of Amphotericin B Solubilised in 2-Hydroxypropyl-γ-Cyclodextrins Possess an Extended Physicochemical Stability? [PDF]
Pharmaceutics, 2020 Chennell P +6 more
europepmc +1 more source
Wireless blood pressure sensor implantation in sheep: A detailed technique
Animal Models and Experimental Medicine, EarlyView.Twelve adult sheep underwent wireless blood pressure sensor implantation. The procedure lasted an average of 36 min, with mean systolic and diastolic blood pressures of 93 ± 6 and 65 ± 5 mmHg, respectively. This rapid, minimally invasive protocol is a powerful platform for cardiovascular device development.
David Santer +10 more
wiley +1 more source
Comparative analysis of delivery of primary eye care in three European countries [PDF]
--
Jahn, Rebecca +4 more
core
Animal Models and Experimental Medicine, EarlyView.Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee +3 more
wiley +1 more source
Efficacy of azithromycin 1% and 1.5% ophthalmic solutions compared to tobramycin 0.3% eye drops: A systematic review and meta-analysis. [PDF]
SAGE Open Med, 2020 Alemu BM, Worku T.
europepmc +1 more source
Animal Models and Experimental Medicine, EarlyView.Steroid‐induced ocular hypertension is a useful mouse model for glaucoma, but published work rarely quantifies how route, dose, and schedule shape the intraocular pressure (IOP) time‐course—hindering reproducibility and forcing labs to pilot protocols.
Nicholas Y. Q. Tan +4 more
wiley +1 more source
Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects
Animal Models and Experimental Medicine, EarlyView.Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu +12 more
wiley +1 more source
Comparative evaluation of Latanoprostene Bunod, Timolol Maleate, and latanoprost Ophthalmic Solutions to assess their safety and efficacy in lowering intraocular pressure for the management of Open-Angle Glaucoma. [PDF]
Clinics (Sao Paulo), 2020 Wang Y, Liao Y, Nie X.
europepmc +1 more source