Results 121 to 130 of about 2,806,264 (293)

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard   +3 more
wiley   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

open access: yesEye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Clinical Benefits of Preservative-Free Treatment for Glaucoma with a Focus on Preservative-Free Latanoprost

open access: yesOphthalmology and Therapy
Purpose To highlight the clinical benefits of preservative-free topical therapies in the management of glaucoma, with a focus on preservative-free latanoprost, and their role in improving ocular surface health and long-term treatment outcomes.
Deepinder K. Dhaliwal   +4 more
doaj   +1 more source

Artificial Intelligence in Optical Coherence Tomography‐Based Ophthalmic Imaging: From Automated Diagnosis to Personalized Disease Monitoring

open access: yesEye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is increasingly applied to optical coherence tomography (OCT) in ophthalmology, but evidence for automated diagnosis is stronger than evidence for longitudinal monitoring. This narrative review evaluates OCT‐based AI with emphasis on disease monitoring and progression, particularly in retinal disease and glaucoma ...
Stjepan Škudar
wiley   +1 more source

Ophthalmic route of drugs administration

open access: yes, 2018
Ophthalmic drug administration becomes increasingly growing researched field in medicine over the years. A wide variety of drug can be administered to and through the eye which can serve as a treatment for a lot of diseases or condition of the eye ...
Bagdadi, Doron
core  

Artificial intelligence technology in ophthalmology public health: current applications and future directions

open access: yesFrontiers in Cell and Developmental Biology
Global eye health has become a critical public health challenge, with the prevalence of blindness and visual impairment expected to rise significantly in the coming decades.
ShuYuan Chen, Wen Bai, Wen Bai
doaj   +1 more source

Artificial Intelligence for Distinguishing Glaucoma From Its Mimickers: A Narrative Review of Diagnostic Pitfalls, Validation Gaps, and Clinical Translation

open access: yesEye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) has advanced rapidly in glaucoma, but many models remain optimized for case‐control detection rather than the clinically harder task of distinguishing glaucoma from its mimickers. This narrative review primarily examined literature published from January 2018 to March 2026 on glaucoma AI, difficult comparator ...
Cansu Yüksel Elgin
wiley   +1 more source

Understanding and safely using ophthalmic lasers

open access: yes, 2016
Ophthalmic lasers allow precise treatment of a range of eye problems with little risk of infection. Many laser procedures are relatively pain free and can be performed on an outpatient basis.
Ismael Cordero
core  

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

open access: yesEpilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer   +7 more
wiley   +1 more source

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