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Contact Dermatitis to Ophthalmic Solutions: An Update

Dermatitis®, 2023
Eyelid and periorbital dermatitis remains a distressing and recalcitrant disease. Contact dermatitis remains the most common cause of eyelid and periorbital dermatitis. Ophthalmic solutions used in the treatment of ophthalmic conditions can often be the cause.
Sally J. Ashton, Avad A. Mughal
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STABILITY OF PENICILLIN IN OPHTHALMIC SOLUTIONS

Archives of Ophthalmology, 1947
IN THE past year several reports have been made concerning the stability of penicillin in solution or in ointment mixture. Gots and Glazer 1 found that specimens of solution and ointment containing 1,000 units per cubic centimeter remain active for approximately one month at room temperature. Kirby 2 found "considerable activity" in an istonic solution
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The Preparation of Sterile Ophthalmic Solutions

Journal of the American Pharmaceutical Association (Practical Pharmacy ed.), 1953
The authors describe an aseptic technique which has been designed to provide the pharmacist with an inexpensive and convenient method of preparing small volumes of sterile solutions in the pharmacy.
Eugene L. Parrott   +2 more
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METHOD FOR THE MAINTENANCE OF STERILITY OF OPHTHALMIC SOLUTIONS

Archives of Ophthalmology, 1947
It is well known that the majority of ophthalmic surgeons are suspicious of the sterility of the ophthalmic solutions presented for use during the course of a surgical procedure on the eye and in the postoperative care. This skeptical attitude extends from the confines of the smallest community or private hospital to the marble halls of the greatest ...
Carl F. Jensen, Gilbert N. Haffly
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EFFECT OF REACTION ON OPHTHALMIC SOLUTIONS

Archives of Ophthalmology, 1933
The effect of drugs introduced into the conjunctival sac in the form of solutions is modified by a number of factors. One of the most important of these is their immediate dilution by tears always present in the sac and by those which rapidly reach it in response to the stimulation afforded by any chemical irritant.
Sanford R. Gifford, R. Denton Smith
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Evaluation of a new preoperative ophthalmic solution

Canadian Journal of Ophthalmology, 2005
Maximum mydriasis and corneal clarity during intraocular surgery are important to ensure operational safety. However, repeated instillation of mydriatic and anti-inflammatory ophthalmic solutions during surgery may affect compliance and may damage the corneal epithelium.
Yuko Kamei   +4 more
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Influence of Ophthalmic Solutions on Tear Components

Cornea, 2016
Tear fluids are a mixture of secretions derived from lacrimal glands, accessory lacrimal glands, conjunctiva, and meibomian glands. Compositional changes to tears occur in the normal state and during ocular surface disease, such as dry eye conditions. We have investigated compositional changes to tears after topical application of ophthalmic solutions,
Masakazu Yamada   +2 more
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Self-Sterilizing Ophthalmic Solutions

Journal of the American Pharmaceutical Association (Practical Pharmacy ed.), 1953
Phenylmercuric nitrate and benzalkonium chloride, in proper solutions are are recommended as effective antibacterial agents for ophthalmic medication.
Harry W Hind, Ivan J. Szekely
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PREPARATION AND MAINTENANCE OF STERILE OPHTHALMIC SOLUTIONS

Journal of the American Medical Association, 1953
Serious ocular infections resulting from the use of contaminated ophthalmic solutions are becoming increasingly prevalent. This situation may be directly attributed to the astounding fact that in the United States, until recently,1no section of the Federal Food, Drug, and Cosmetic Act was interpreted as requiring manufacturers and dispensers of eye ...
Robert R. Feinstein   +1 more
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Ketorolac 0.45% Ophthalmic Solution

Drugs & Aging, 2011
Ketorolac 0.45% ophthalmic solution is a topical NSAID indicated in the US for the treatment of ocular pain and inflammation following cataract surgery. In animal studies, the ocular relative bioavailability of single-dose topical ketorolac 0.45% ophthalmic solution was 2- to 3-fold higher than that of ketorolac 0.4% ophthalmic solution.
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