Results 261 to 270 of about 20,308 (302)
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Buffered Ophthalmic Solutions of Silver Nitrate*
Journal of the American Pharmaceutical Association (Scientific ed.), 1955One per cent silver nitrate solutions have been prepared in an acetate buffer at pH 6.0 and have been shown to remain stable for as long as two years.A simple colorimetric method using bromcresol purple as the indicator has been used to detect increased acidity in the solutions.This dye is especially sensitive in the range of pH 5.8 to 6.0, the ...
Walter F. Charnicki, Mary L. Kober
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Extemporaneous Preparation of Antibiotic Ophthalmic Solutions
Journal of the American Pharmaceutical Association (1996), 1996Until the introduction of ocular ciprofloxacin, the standard of practice in treating bacterial corneal ulcers required topical antibiotic ophthalmic solutions that were either not commercially available or not available in the higher concentrations needed.
Raymond W. Hammond +3 more
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Quantitative Determination of Pilocarpine in Ophthalmic Solutions
Journal of Pharmaceutical Sciences, 1965A method is described for the quantitative determination of pilocarpine in ophthalmic solutions. It is based on reaction with hydroxylamine in an alkaline medium to give the hydroxamic acid, which is complexed with ferric ion. Although the color produced is relatively unstable, the method has a high degree of precision if the experimental conditions ...
Joseph D. Benmaman +2 more
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The Clinical Significance of the pH of Ophthalmic Solutions*,†
Journal of the American Pharmaceutical Association (Scientific ed.), 1953Abstract The clinical significance of the p H of ophthalmic solutions was determined by intrasubject comparison of the pharmacologic effects of drug solutions differing only with regard to their p H. For pilocarpine and ephedrine the conclusion was reached that the clinical significance of the p H of the vehicle was small unless the vehicle was ...
Peter C. Kronfeld +2 more
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An Evaluation of Chemical Preservatives for Ophthalmic Solutions*
Journal of the American Pharmaceutical Association (Scientific ed.), 1955Data are presented on the relative antimicrobial activities of seven commonly used chemical compounds that are used for preserving ophthalmic drug solutions from Pseudomonas and Proteus contaminations. In testing the compounds against 26 strains of Pseudomonas aeruginosa and four species of Proteus in a simple buffer solution, in the absence of an ...
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THE pH AND TONICITY OF OPHTHALMIC SOLUTIONS
Archives of Ophthalmology, 1943The hydrogen ion concentration of the solution in which an ophthalmic drug is dissolved may alter the therapeutic results of the drug itself. A variation of thepHoften determines the speed and the quantity of absorption of the drug and the amount of irritation which the patient experiences on instillation.
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Medical Journal of Australia, 1976 THE STABILITY OF ADRENALINE OPHTHALMIC SOLUTIONS ON STERILIZATION AND STORAGE
Journal of Clinical Pharmacy and Therapeutics, 1982The stability of adrenaline ophthalmic solutions, at pH 5.8 and 7.4, to sterilization and storage conditions has been studied. Solutions sterilized by filtration or heating at 98 degrees C for 30 min showed no detectable degradation at either pH value, whilst sterilization at higher temperatures resulted in losses of up to 30%.
Sixsmith, DG, Watkins, WM, Kokwaro, GO
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METHYL CELLULOSE SOLUTION FOR OPHTHALMIC USE
Archives of Ophthalmology, 1951THE USE of methyl cellulose solutions in ophthalmology is growing daily.1Because there is a variation in the concentrations recommended for use, as reported in the literature, my associates and I have tried to determine the concentration of methyl cellulose which would be most satisfactory and the proper composition of solutions of this substance.
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