Results 111 to 120 of about 8,467 (285)

Advanced therapy medicinal products (ATMPs) – An analysis of the global regulatory status

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background A rapid progress in the development of advanced therapy medicinal products (ATMPs) has taken place over the past decades. The ATMPs hold great potential but face challenges in the clinical development and the regulatory process.
Allan Cramer   +4 more
wiley   +1 more source

Sutureless Cataract Surgery: Principles and Steps

open access: yesCommunity Eye Health Journal, 2003
Introduction. Cataracts cause about 50% of world blindness. There is little likelihood of effective prevention becoming available in the next few years and so the only treatment will remain surgical. For many of the other major causes of world blindness,
John Sandford-Smith
doaj  

Clinical and surgical data of affected members of a classic CFEOM I family.

open access: yes, 2003
BACKGROUND: Congenital fibiosis of the extraocular muscles (CFEOMI) refers to a group of congenital eye movement disorders that are characterized by non-progressive restrictive ophthalmoplegia. We present clinical and surgical data on affected members
Gagliardi V.   +3 more
core  

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

open access: yesBMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu   +7 more
wiley   +1 more source

Bilaterale anteriore ischämische Optikusneuropathie nach EHEC-Sepsis und hämolytisch-urämischem Syndrom

open access: yes, 2013
After emerging from a coma caused by enterohemorrhagic Escherichia coli (EHEC) sepsis with severe neurological and renal involvement a 53-year-old female patient complained of blurred vision.
Hufendiek, K., Jägle, H., Wortmann, T.
core   +1 more source

Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley   +1 more source

Mosaic activation of the zebrafish hsp70l heat shock promoter: Implications for interpreting transgenes

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley   +1 more source

Comparing the preventive effect of 2 percent Topical Lidocaine and Intravenous Atropine on oculocardiac reflex in Ophthalmological Surgeries under General Anesthesia

open access: yesInternational Journal of Preventive Medicine, 2013
Background: The current study aimed to determine preventive effect of 2 percent topical xylocaine on oculocardiac reflex in ophthalmological surgeries except strabismus, including retinal detachment and vitrectomy with scleral buckling under general ...
Parvin Sajedi   +3 more
doaj  

A Case Report on use of Topical Insulin Therapy for Persistent Epithelial Defects in Stevens-Johnson Syndrome

open access: yesJournal of Clinical and Diagnostic Research
Persistent Epithelial Defects (PED) in Stevens-Johnson Syndrome (SJS) pose significant challenges in ophthalmic management. This case highlights the use of topical insulin therapy as a novel treatment for PED in a 59-year-old female with SJS-associated ...
Sumit Navneet Toshniwal   +3 more
doaj   +1 more source

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