Results 91 to 100 of about 85,637 (309)

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Efficacy of 0.01% atropine for myopia control in children: an artificial intelligence-assisted multivariate Bayesian meta-analysis

Frontiers in Medicine
BackgroundLow-concentration atropine (0.01%) has been widely investigated as a safe intervention for myopia control in children, yet its true efficacy remains uncertain due to inconsistent trial findings and high heterogeneity.MethodsAn artificial ...
Like Zhang, Xiao Chen, Xiujing Deng, Xiaobing Wang, Ran Chen   +4 more
doaj   +1 more source

Neuro-ophthalmological manifestations of Behçet’s disease

, 2018
BackgroundThe neuro-ophthalmological manifestations of Behcet’s disease (BD) are rare, and data regarding their characteristics and outcome are lacking.ObjectiveTo report prevalence, main characteristics and outcome of neuro-ophthalmological ...
Comarmond, Chloé, Patrice Cacoub, Domont, Fanny, Saadoun, David, Depaz, Raphael, Alghamdi, Ammr, Fanny Domont, Phuc Le Hoang, Ammr Alghamdi, Bodaghi, Bahram, Chloé Comarmond, Le Hoang, Phuc, David Saadoun, Raphael Depaz, Bahram Bodaghi, Cacoub, Patrice, Valérie Touitou, Desbois, Anne Claire, Wechsler, Bertrand, Bertrand Wechsler, Anne Claire Desbois, Touitou, Valérie   +21 more
core   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source

Success predictors of selective laser trabeculoplasty in primary angle-closure glaucoma: a long-term follow-up

Российский офтальмологический журнал, 2019
Purpose. To evaluate the effectiveness and the factors predictive of long-term failure of selective laser trabeculoplasty (SLT) in patients with the initial stage of primary angle-closure (PACG) and primary open angle glaucoma (POAG).Materials and ...
N. I. Kurysheva, L. V. Lepeshkina, E. O. Shatalova   +2 more
doaj   +1 more source

Ophthalmological Findings in Paediatric and Adolescent Multiple Sclerosis

, 2012
Background: Multiple sclerosis (MS) is a chronic demyelinating disorder of the central nervous system of unknown aetiology. The onset of MS in childhood poses diagnostic and therapeutic challenges.
Ababneh, L., Pfriem, M., Schittkowski, Michael P.   +2 more
core   +1 more source

Pimasertib-associated ophthalmological adverse events [PDF]

, 2018
To analyse ophthalmological adverse events associated with mitogen-activated protein kinase kinase (MEK) inhibition with pimasertib treatment for metastatic cutaneous melanoma (CM).
Gregorius P.M. Luyten, Elon H.C. van Dijk, Boon, Camiel J. F., Luyten, G.P.M., Johannes R. Vingerling, Jager, M.J., Boon, C.J.F., Dijk, EHC, van Dijk, Elon H. C., Luyten, Gregorius P. M., Jager, Martine J., Kruit, Wim, Kruit, W.H.J., Vingerling, Johannes R., Camiel J.F. Boon, Boon, CJF, Martine J. Jager, Wim H.J. Kruit, Dijk, E.H.C. van, Vingerling, Hans, Jager, MJ, Kruit, Wim H. J., Vingerling, J.R., Luyten, GPM   +23 more
core   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Long-Term Follow-Up of Intrastromal Corneal Ring Segments in Paracentral Keratoconus with Coincident Corneal Keratometric, Comatic, and Refractive Axes: Stability of the Procedure

Journal of Ophthalmology, 2017
Purpose. To assess the long-term outcomes of implanting intrastromal corneal ring segments (ICRS) in paracentral keratoconic eyes. Methods. 58 eyes with paracentral keratoconus with coincident refractive, keratometric, and comatic axes were evaluated ...
Luis Fernández-Vega Cueto, Carlos Lisa, David Madrid-Costa, Jesús Merayo-Lloves, José F. Alfonso   +4 more
doaj   +1 more source

HYPERTHYROIDISM AND GRAVES' DISEASE: OPHTHALMOLOGICAL MANIFESTATIONS AND SURGICAL TREATMENT. [PDF]

Introduction: Hyperthyroidism, characterized by the excessive production of hormones by the thyroid gland, can lead to various systemic complications, including ophthalmological manifestations such as Graves' Orbitopathy (GO). Graves' Disease, one of the
Amaro, Lara Lacerda, Martins, Pedro Felipe Rezende, Almeida, Pedro da Costa Siqueira de, Cruz, Rayane Alves, Santos, Luan Bernardino Montes, Barros, Layla Azevedo Alencastro Cupertino de, Correa, Stefanny Machado, Alencar, Dayanne Soares, Rodrigues, Matheus do Carmo, Costa, Thelma da, Oliveira, Gabriel Nojosa, Ribeiro, Pedro Henrique Rodrigues   +11 more
core   +1 more source