Results 41 to 50 of about 6,763,607 (280)

How to assess a patient for glaucoma

Community Eye Health Journal, 2006
IntroductionGlaucoma affects approximately 65 million people around the world and an expected 7.5 million are blind due to the disease. It is the second most common cause of blindness worldwide.1 It is estimated that perhaps half the blindness from ...
Rajul S Parikh, Ravi Thomas
doaj  

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

Advanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang, Xinxing Wang, Lianfeng Xie, Wenna Ding, Yingyong Yin, Mei Yao, Zhibo Cui, Kaiqiang Tang, Lijie Zhong, Zhi Wang, Jia Wang, Lei Lei, Xiaoxiao Qu, Chi‐E. Qiu   +13 more
wiley   +1 more source

Patient demographics and ophthalmological parameters.

, 2019
Patient demographics and ophthalmological parameters.
Yukari Tsuneyoshi (6281984), Kenya Yuki (601807), Kazuno Negishi (848094), Masahiko Ayaki (4621612), Kazuo Tsubota (247512)   +4 more
core   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Sutureless Cataract Surgery: Principles and Steps

Community Eye Health Journal, 2003
Introduction. Cataracts cause about 50% of world blindness. There is little likelihood of effective prevention becoming available in the next few years and so the only treatment will remain surgical. For many of the other major causes of world blindness,
John Sandford-Smith
doaj  

Diagnostic methods and therapeutic options of uveal melanoma with emphasis on MR imaging—Part I: MR imaging with pathologic correlation and technical considerations

Insights into Imaging, 2021
Uveal melanoma is a malignant neoplasm that derives from pigmented melanocytes of the uvea and involves, in order of decreasing prevalence, the choroid, ciliary body and iris.
Pietro Valerio Foti, Mario Travali, Renato Farina, Stefano Palmucci, Corrado Spatola, Luigi Raffaele, Vincenzo Salamone, Rosario Caltabiano, Giuseppe Broggi, Lidia Puzzo, Andrea Russo, Michele Reibaldi, Antonio Longo, Paolo Vigneri, Teresio Avitabile, Giovani Carlo Ettorre, Antonio Basile   +16 more
doaj   +1 more source

Spatially Confined/Ligand‐Directed Ultrabright NIR‐AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis

Advanced Science, EarlyView.
Inorganic PbS quantum dots spatially confine AIEgens and enable cooperative luminescence within a ligand‐directed core–shell–shell nanoassembly, generating ultrabright NIR PPANPs with enhanced fluorescence and photothermal performance. The platform enables 10‐min S.
Yujian Li, Jia Shu, Sijia Lv, Leilei Qin, Xuefeng Luo, PengCheng Xiao, Huan Cai, Xin Gao, Yan Zhao, Haotian Zhou, Yaji Yang, Zhenglin Zhu, Shijia Ding, Juan Li, Rui Chen, Wei Huang   +15 more
wiley   +1 more source

Diagnostic Accuracy of Ultrasound in Detection of Traumatic Lens Dislocation

Emergency, 2014
Introduction: Traumatic eye injuries (TEI) involved about 3% of cases referred to the emergency departments of developing countries. Lens dislocation is one of the critical cases of ophthalmic emergencies.
Seyed Hossein Ojaghi Haghighi, Hamid Reza Morteza Begi, Raana Sorkhabi, Mohammad Kazem Tarzamani, Golshan Kamali Zonouz, Akram Mikaeilpour, Farzad Rahmani   +6 more
doaj  

Case Report of Schnyder Corneal Dystrophy—A Rare Lipid Metabolic Disorder of the Cornea

Life
Background: Schnyder corneal dystrophy (SCD) is a rare autosomal dominant disorder characterized by bilateral corneal opacification due to abnormal cholesterol and phospholipid deposition.
Nina Stoyanova, Abdulrahman Imran, Zain Ul Hassan, Krasimir Kraev, Yordanka Basheva-Kraeva, Maria Kraeva, Petar Uchikov, Plamena Novakova, Veselin Vasilev, Ivaylo Minev, Bozhidar Hristov, Desislava Koleva-Georgieva, Petko Petrov, Luboslav Dimov, Svetlan Dermendzhiev, Marin Atanassov   +15 more
doaj   +1 more source