Results 81 to 90 of about 596,683 (351)

Optical Coherence Tomography Abnormalities as the Presenting Sign of an Involuted Sellar/Suprasellar Mass

Case Reports in Ophthalmology
Introduction: Pituitary adenomas are benign tumours that can lead to visual loss through compression of the optic chiasm. Patients with pituitary adenomas often present with visual field defects (commonly bitemporal hemianopia), but some may be ...
Arshia Vosoughi, Jonathan A. Micieli
doaj   +1 more source

Effects of COVID-19 pandemic on stress level of residents and fellows during ophthalmology training

, 2022
Itamara O Aragão, Tatiana G C Alencar, Ana Karine A Soares, Camilla Rocha, Camila V Ventura   +4 more
openalex   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Assessment of Intraocular Pressure Measurement Between Goldmann Applanation Tonometer and Portable Non-Contact Tonometer (TH1U)

Clinical Ophthalmology
Xianyao Peng, Jiahui Wang, Jiaqi Chen, Yinan Wu, Tianyu Wang, Wuliang Li, Xiaoping Xu Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, People’s Republic of ...
Peng X, Wang J, Chen J, Wu Y, Wang T, Li W, Xu X   +6 more
doaj  

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Antifouling All‐Polymeric Microneedle Array for Long‐Term Wearable ECG Monitoring

Advanced Science, EarlyView.
A biocompatible, all‐polymeric MNEs designed for long‐term ECG monitoring is developed. Coated with PEDOT:Tos and zwitterionic SBMA, the MNEs offer ultra‐low impedance and antifouling properties. After 14 days of continuous use, the MNEs accurately detected PQRST complexes, highlighting its potential for long‐term, real‐time ECG monitoring in everyday ...
Ju Hyeon Kim, Chuljin Hwang, Jee Hoon Lee, Hang Chan Jo, Dae Yu Kim   +4 more
wiley   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Syntaxin 3B Mediates Light‐Dependent Interactions with STXBP1 and Arrestin 4: Distinct Roles in Rods and Cones

Advanced Science, EarlyView.
The present study investigates a cone‐specific STX3 knockout model, displaying a complete loss of cone function, a later onset reduction in rod function, and photoreceptor cell death. A cone‐specific depletion of STXBP1 and ARR4 could be observed in this model.
Lars Tebbe, Larissa Ikelle, Mustafa S. Makia, Mashal Kakakhel, Muayyad R. Al‐Ubaidi, Muna I. Naash   +5 more
wiley   +1 more source

Associations of Sleep Duration and Social Jetlag with Dry Eye Disease in Chinese School-Aged Children and Adolescents

Nature and Science of Sleep
Yuzhu Luo,1,* Yuting Gao,1,* Zhong Guan,1,* Heting Liu,1 Shuman Tao1– 5 1Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, People’s Republic of China; 2MOE Key Laboratory of ...
Luo Y, Gao Y, Guan Z, Liu H, Tao S
doaj  

Efficacy of the Combined Intrastromal Injection of Voriconazole and Amphotericin B in Recalcitrant Fungal Keratitis

Microorganisms
This study aims to report the efficacy of a combined intrastromal injection in optimizing the outcome of severe mycotic keratitis. Herein, we report a case series of 20 consecutive patients with positive fungal cultures not responding to topical ...
Antonio Moramarco, Arianna Grendele, Danilo Iannetta, Simone Ottoboni, Giulia Gregori, Natalie di Geronimo, Margherita Ortalli, Tiziana Lazzarotto, Luigi Fontana   +8 more
doaj   +1 more source