Results 181 to 190 of about 9,186 (248)

Chronic progressive external ophthalmoplegia

Acta Ophthalmologica, 2022
AbstractChronic progressive external ophthalmoplegia (CPEO) is an array of genetic condition which causes progressive paralysis of the extraocular muscles and lid ptosis. CPEO can occur in isolation or in association with other systemic features (CPEO‐plus) including myopathy, dysarthria, ataxia, and parkinsonism.
R. Karanjia
openaire   +2 more sources

CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA

Brain, 1975
The clinical features and investigative findings of 50 patients with chronic progressive external ophthalmoplegia (CPEO) were analysed. The group was found to be clinically, genetically and histologically heterogeneous. With the possible exception of patients with "ophthalmoplegia plus," namely those who in addition to muscular weakness had evidence of
G, Danta, R C, Hilton, P G, Lynch
openaire   +4 more sources

Chronic progressive external ophthalmoplegia

Current Neurology and Neuroscience Reports, 2002
Chronic progressive external ophthalmoplegia (CPEO) is a descriptive term for a heterogenous group of disorders characterized by chronic, progressive, bilateral, and usually symmetric ocular motility deficit and ptosis. Significant pain, proptosis, or pupil involvement are not features of CPEO and should prompt evaluation for alternative etiologies ...
Andrew G, Lee, Paul W, Brazis
openaire   +2 more sources

Chronic progressive external ophthalmoplegia plus syndrome due to homozygous missense variant in TOP3A gene

Clinical Genetics, 2022
Chronic progressive external ophthalmoplegia (CPEO) plus syndrome due to pathogenic biallelic variants in TOP3A gene has been described in only one single patient.
A. Llauradó, E. Rovira-Moreno, M. Codina-Solà, E. Martínez-Sáez, M. Salvadó, D. Sánchez-Tejerina, J. Sotoca, V. López-Diego, J. L. Restrepo-Vera, E. García-Arumí, R. Juntas-Morales   +10 more
semanticscholar   +1 more source

Persistent Corneal Defect in Chronic Progressive External Ophthalmoplegia

Journal of Medical Optometry, 2023
This unique case highlights the difficulties of managing both CPEO and the complications related to the ocular surface and adnexa, including...
John Conto, Jane Bachman Groth
semanticscholar   +1 more source

Müller Muscle-Conjunctival Resection With Tarsectomy in Chronic Progressive External Ophthalmoplegia.

The Journal of craniofacial surgery (Print)
This report presents 2 cases of chronic progressive external ophthalmoplegia (CPEO) with progressive bilateral ptosis, managed successfully using Müller muscle-conjunctival resection with tarsectomy (MMCRT).
M. Mangan, Emirhan Ozkul, C. Arıcı, Seda Mazmanoglu Atilman   +3 more
semanticscholar   +1 more source

Pearls and Oy-sters: Chronic Progressive External Ophthalmoplegia With Electrical Myotonia and Negative Initial Genetic Testing.

Neurology
Chronic progressive external ophthalmoplegia (CPEO), a genetic syndrome characterized by slowly progressive paresis of extraocular muscles, is often due to single large-scale deletions of the mitochondrial genome (mtDNA).
Brian Y Li, Julia H Greenberg, Connolly G Steigerwald, Renkui Bai, K. Tanji, Elina Zakin, Nicolas J. Abreu   +6 more
semanticscholar   +1 more source

Chronic Progressive External Ophthalmoplegia

Archives of Ophthalmology, 1969
The syndrome of chronic progressive external ophthalmoplegia has been generally regarded as denoting an ocular myopathy. Recent evidence is presented, however, which both denies the universality of a myopathic etiology and demonstrates our present inability to distinguish between myopathy and neural weakness of ocular muscles.
openaire   +2 more sources

Surgical management of ptosis in chronic progressive external ophthalmoplegia

European Journal of Ophthalmology, 2020
Purpose: To determine possible complications and efficacy of ptosis surgery in a series of chronic progressive external ophthalmoplegia (CPEO) patients with healthy tear film.
M. Eshaghi, A. Arabi, Sarvin Eshaghi
semanticscholar   +1 more source