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Opiates

2023
Opiates are both therapeutical and illicit drugs used by the population. Notwithstanding the introduction of new psychoactive substances (NPS), in particular of new derivatives of fentanyl, opiates and heroin in particular, represents one of the most diffused illicit drug and still accounts for most of the seizures worldwide.
Pascali, Jennifer P. and Fais, Paolo
openaire   +3 more sources

The Clinical Opiate Withdrawal Scale (COWS)

Journal of Psychoactive Drugs, 2003
D. Wesson, W. Ling
exaly   +2 more sources

The Opiate Receptors [PDF]

open access: possibleAnnual Review of Pharmacology and Toxicology, 1978
The extract of the opium poppy is among the oldest materials used for medicinal purposes, and the study of the major alkaloid in this extract, morphine. is one of the oldest areas of biological research. Our lack of understanding on the molecular level of how morphine and its analogues produce their effects may be in large part related to the fact that
Eric J. Simon, Jacob M. Hiller
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Opiate treatment for opiate withdrawal in newborn infants

Cochrane Database of Systematic Reviews, 2002
Neonatal abstinence syndrome (NAS) due to opiate withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss and seizures. Treatments used to ameliorate symptoms and reduce morbidity include opiates, sedatives and non-pharmacological treatments.To assess the effectiveness and safety
Heather E. Jeffery   +2 more
openaire   +5 more sources

Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK General Practice Research Database

open access: yesBMJ: British Medical Journal, 2010
Objective To investigate the effect of opiate substitution treatment at the beginning and end of treatment and according to duration of treatment. Design Prospective cohort study.
Rosie Cornish, John Strang, M Hickman
exaly   +2 more sources

Opiate receptors and endogenous opiates: Panorama of opiate research

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1982
1. In the last ten years basic research on the mechanism of action of opiates has led to the clearcut demonstration of the existence of opiate receptors--possibly several slightly different kinds--in the nervous system. 2. A number of endogenous ligands also called endorphins or enkephalins for these receptors have been discovered that proved to be ...
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Opiates and plasticity

Neuropharmacology, 2011
Opiates are among the most powerful analgesics and pain-relieving agents. However, they are potentially extremely addictive thereby limiting their medical use, making them exceedingly susceptible to abuse and adding to the global drug problem. It is believed that positive memories associated with the pleasurable effects of opiates and negative memories
Dacher, Matthieu, Nugent, Fereshteh S.
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Opiates and infection

Journal of Neuroimmunology, 1998
This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. There is both increased prevalence and increased severity of bacterial and viral infections in injection drug users with the outcome of ...
Phillip K. Peterson   +3 more
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Autoanalgesia: Opiate and non-opiate mechanisms

Neuroscience & Biobehavioral Reviews, 1980
Autoanalgesia (behaviorally-activated antinociception) was elicited by lesion-induced hyperemotionality or the classical conditioning of fear to the environmental stimuli associated with measuring antinociception. Both hyperemotionality and antinociception exhibited parallel decline in septal-lesioned rats with daily handling and in VMH-lesioned rats ...
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