Results 121 to 130 of about 764,854 (215)

Process evaluation of an effective Antimicrobial Stewardship intervention in hospitalized patients with community-acquired pneumonia. [PDF]

open access: yesAntimicrob Steward Healthc Epidemiol
van Heijl I   +6 more
europepmc   +1 more source

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

open access: yesAdvanced Science, EarlyView.
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie   +17 more
wiley   +1 more source

Polyelectrolyte Design Principles for Electrophoretic Drug Delivery

open access: yesAdvanced Science, EarlyView.
Structure–property–function mapping of polyelectrolytes reveals how composition and nanoscale order control on‐demand electrophoretic drug transport. Charge density quantified under implant‐relevant conditions shows that encapsulation limits swelling, enabling high effective charge density.
Helena Saarela Unemo   +8 more
wiley   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

open access: yesAdvanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia   +4 more
wiley   +1 more source

Assessment of two feed additives consisting of <i>Lactiplantibacillus plantarum</i>ATCC PTA-6139 and <i>Lacticaseibacillus paracasei</i>ATCC PTA-6135 for all animal species (Pioneer Hi-Bred International, Inc). [PDF]

open access: yesEFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +17 more
europepmc   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Associations between inclusivity norms and tolerance, contact, and cooperation amid polarization: Evidence from 12 European countries. [PDF]

open access: yesPNAS Nexus
Schäfer LF   +23 more
europepmc   +1 more source

Multi‐scale Optimization on Interfacial Evaporative Cooling for Photovoltaic Performance Enhancement

open access: yesAdvanced Science, EarlyView.
This study presents a passive siphon‐driven interfacial evaporative cooling technology for photovoltaics. A multiscale multiphysics model is developed and validated experimentally. Results show that optimizing installation parameters reduces operating temperature by up to 22.3 °C and boosts power efficiency by 8.9%, offering a practical pathway for ...
Fuxiang Li   +5 more
wiley   +1 more source

Bone age assessment: comparative analysis of Greulich-Pyle and Tanner-Whitehouse 3 by pediatric radiologists and endocrinologists. [PDF]

open access: yesBMC Med Imaging
Tewattanarat N   +9 more
europepmc   +1 more source

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