Results 31 to 40 of about 10,879 (196)

Topical Morphine Gel as a Systemic Opioid Sparing Technique

Journal of Pain & Palliative Care Pharmacotherapy, 2022
Use of topical morphine gel was explored retrospectively for treatment of painful chronic wounds in hospitalized adults. Systemic opioid use and pain intensity were characterized before and after morphine gel initiation using morphine equivalent daily dose (MEDD) and the Defense and Veterans Pain Rating Scale (DVPRS) score at 24 hours before compared ...
Rachel C. Klosko, Maureen L. Saphire
openaire   +2 more sources

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Intermittent Boluses of Local Anesthetic Through Quadratus Lumborum Catheters for Analgesia in a Living Donor Hepatectomy

Case Reports in Anesthesiology, 2019
The demand for liver transplants in the United States far exceeds the supply of organs. As need has increased, so has use of living donors. Coagulopathy and various side effects often preclude the use of neuraxial regional techniques and opioids for ...
Shelly B. Borden, Molly K. Groose, Eric R. Simon, Aaron S. Hess, Kristopher M. Schroeder   +4 more
doaj   +1 more source

Ultrasound‐Guided Liposomal vs. Conventional Bupivacaine Erector Spinae Plane Block Plus Gabapentin for Postherpetic Neuralgia

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu, Li‐Juan Liu, Fa‐Ming Xu, Xiang‐Yu Fang   +3 more
wiley   +1 more source

Traditional Chinese Medicine as an Integrative Adjunct in Oncology Perioperative Practice: Analgesia, Immune Modulation, and Translational Challenges

Medicine Bulletin, EarlyView.
ABSTRACT Traditional Chinese medicine (TCM), including herbal analgesic adjuvants and acupuncture‐based interventions, has gained increasing attention as an integrative strategy for perioperative pain management in oncology. Bioactive phytochemicals—such as terpenoids, flavonoids, alkaloids, and polyphenols—exert multimodal pharmacological effects ...
Yuqin Tang, Zheng Luo, Xu Zhao, Yongqiang Zhang, Mingyang Sun, Jiaqiang Zhang   +5 more
wiley   +1 more source

Multimodal analgesia with parasternal plane block protocol within an enhanced recovery after cardiac surgery program decreases opioid useCentral MessagePerspective

JTCVS Open
Objective: This study investigated the efficacy of a multimodal analgesia (MMA) with an opioid-sparing strategy, incorporating a parasternal plane block (PPB) within a systematic standardized Enhanced Recovery After Surgery (ERAS) program for patients ...
Marc Darras, MD, Clément Schneider, MD, Sandrine Marguerite, MD, Saadé Saadé, MD, Anne-Lise Maechel, MD, Walid Oulehri, MD, Olivier Collange, MD, PhD, Jean-Philippe Mazzucotelli, MD, PhD, Paul-Michel Mertes, MD, PhD, Michel Kindo, MD, PhD   +9 more
doaj   +1 more source

Inpatient Opioid Use in Head and Neck Microvascular Free Flap Reconstruction

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objectives The primary objective is to determine whether patients undergoing osseous microvascular free flap reconstruction of head and neck defects have higher inpatient pain requirements than those undergoing nonosseous reconstruction. Secondary aims include evaluating the impact of a multimodal analgesia (MMA) protocol and COVID‐19 visitor ...
Patricia Timothee, Alessandra Bliss, Daniel Blumenthal, John Dowd, Emily Clementi, Bruce Davidson, Michael Reilly, Matthew Pierce, Jonathan Giurintano   +8 more
wiley   +1 more source

Postoperative pain and pain management and neurocognitive outcomes after non-cardiac surgery: a protocol for a series of systematic reviews

Systematic Reviews, 2022
Background Postoperative delirium (POD) is common after non-cardiac surgery in older adults and can result in increased risk of adverse outcomes including postoperative cognitive dysfunction (POCD).
Maram Khaled, Denise Sabac, Maura Marcucci   +2 more
doaj   +1 more source

Intravenous paracetamol does not have significant opioid‐sparing effects when used as part of a multimodal analgesic protocol in dogs undergoing elective orthopaedic surgery

Veterinary Record, EarlyView.
Abstract Background Data evaluating paracetamol combined with NSAIDs in dogs are scarce. Results of clinical studies in dogs investigating intravenous paracetamol vary. Methods Dogs were randomised to either receive 10 mg/kg paracetamol intravenously after induction of anaesthesia and every 8 hours during hospitalisation (test) or not (control).
Robin Stallard, Julia Deutsch, Joanna Murrell   +2 more
wiley   +1 more source

AAKD: A standardized and comprehensive acupuncture anesthesia knowledge platform for enhanced recovery after surgery and mechanism

VIEW, EarlyView.
Acupuncture anesthesia (AA) is an application of acupuncture innovation in surgical operations, combined with anesthetic techniques, and is a model of integrated Chinese and Western medicine. We proposed the Acupuncture Anesthesia Knowledge Database (AAKD), in which all data have been meticulously curated by field experts and assessed by a multi ...
Ying Wang, Honglian Huang, Chenchen Feng, Xueli Zhang, Weiting Wang, Ziyi Wei, Jing Li, Xintong Yu, Hanzhi Lu, Chunfang Gao, Ke Wang, Jia Zhou   +11 more
wiley   +1 more source