Results 151 to 160 of about 1,505,677 (242)

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco   +5 more
wiley   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri   +5 more
wiley   +1 more source

The opioid crisis and British prisons [PDF]

open access: yesCriminal Behaviour and Mental Health, 2019
Rob Poole   +2 more
openaire   +2 more sources

A Dynamic Model of Opioid Overdose Deaths in Canada during the Co-Occurring Opioid Overdose Crisis and COVID-19 Pandemic

open access: yes
With over 40,000 opioid-related overdose deaths between January 2016 and June 2023, the opioid-overdose crisis is a significant public health concern for Canada.
Nathaniel D. Osgood   +3 more
core   +1 more source

Government as orchestrator: Ecosystem transformation at scale and speed

open access: yesStrategic Management Journal, EarlyView.
Abstract Research Summary Grand challenges are ecosystem challenges: success depends on aligning a multilateral set of public and private sector actors whose interdependent contributions determine whether a mission is achieved. This study examines how government can orchestrate ecosystem alignment by leveraging distinctive capabilities to deliver ...
Ron Adner
wiley   +1 more source

Investigating SME‐Inclusive Public‐Private AI Innovation Network: Evidence From U.S. Small Business Administration (1991–2023)

open access: yesThunderbird International Business Review, EarlyView.
ABSTRACT Understanding innovation policy is pivotal to enhancing national competitiveness for global value chain. This research investigates an SME‐Inclusive public‐private AI innovation network over time in the U.S. context (1991–2023), revealing how a government's demand‐based innovation policy bolsters technological prowess through isomorphism and ...
Jiyoon An
wiley   +1 more source

Addressing problematic opioid use in OECD countries.

open access: yes, 2019
Key findings • In 25 OECD countries for which data are available, the average of opioid-related deaths (ORD) has increased by more than 20% in 2011-2016, with the rise most pronounced in the United States, Canada, Sweden, Norway, Ireland, and England ...

core  

Single‐dose enflicoxib versus a 7‐day course of firocoxib for postoperative pain control in dogs undergoing orthopaedic surgery: A multicentre, randomised, masked, non‐inferiority study

open access: yesVeterinary Record, EarlyView.
Abstract Background Perioperative analgesia is essential in dogs undergoing orthopaedic surgery, and enflicoxib's long duration makes single‐dose administration attractive. Methods A prospective, multicentre, randomised, masked trial compared enflicoxib (8 mg/kg) given 24 hours before surgery with firocoxib (5 mg/kg) given daily for 7 days. Two hundred
Marta Salichs   +4 more
wiley   +1 more source

Review on enhancing clinical decision support system using machine learning

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
Abstract Clinical decision‐making is a complex patient‐centred process. For an informed clinical decision, the input data is very thorough ranging from detailed family history, environmental history, social history, health‐risk assessments, and prior relevant medical cases.
Anum Masood   +4 more
wiley   +1 more source

The Dark Pyramid: Unpacking the Multidimensional Nature of the Dark Side of Leadership

open access: yesBritish Journal of Management, EarlyView.
Abstract The dark side of leadership has been employed as an umbrella term to cover an array of concepts typically concerned with the dysfunctionality and/or toxicity of individual leaders. As the field of leadership studies moves towards ‘post‐heroic’ perspectives, we apply the same ontological positioning, adopting a ‘post‐villainous’ perspective in ...
Peter Stephenson   +2 more
wiley   +1 more source

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