Results 31 to 40 of about 333,138 (224)

The Rural Opioid Initiative Consortium description: providing evidence to Understand the Fourth Wave of the Opioid Crisis

, 2022
OBJECTIVE: To characterize and address the opioid crisis disproportionately impacting rural U.S. regions. METHODS: The Rural Opioid Initiative (ROI) is a two-phase project to collect and harmonize quantitative and qualitative data and develop tailored ...
Stopka, Thomas J., Friedmann, Peter D., Feinberg, Judith, Westergaard, Ryan P., Tsui, Judith I., Cooper, Hannah L. F., Fredericksen, Rob, Rudolph|, Abby E. Rudolph, Joseph A. C. Delaney, Pho, Mai T., Thomas J. Stopka, Allen, Todd M., P. Todd Korthuis, Todd M. Allen, Hannah L. F. Cooper, Vivian F. Go, Seal, David W., Young, April M., Smith, Gordon S., Wiley D. Jenkins, Gordon S. Smith, Korthuis, P. T., null null, David W. Seal, Crane, Heidi M., Jenkins, Richard A., Miller, William C., Ryan P. Westergaard, Delaney, Joseph A. C., Jenkins, Wiley D., William A. Zule, Judith I. Tsui, Mai T. Pho, Rob Fredericksen, Judith Feinberg, Heidi M. Crane, Rudolph, Abby E., Nance, Robin M., Richard A. Jenkins, Robin M. Nance, Whitney, Bridget M., William C. Miller, Go, Vivian F., Bridget M. Whitney, April M. Young, Peter D. Friedmann, Rudolph, Abby, Korthuis, P. Todd, Zule, William A.   +49 more
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The opioid epidemic and national guidelines for opioid therapy for chronic noncancer pain: a perspective from different continents

PAIN Reports, 2017
. Introduction:. A marked rise in opioid prescriptions for patients with chronic noncancer pain (CNCP) with a parallel increase in opioid abuse/misuse, and resulting deaths was noted in the Unites states in the past decade (opioid epidemic). In response,
Winfried Häuser, Stephan Schug, Andrea D. Furlan   +2 more
doaj   +1 more source

Opioid use disorder and treatment: challenges and opportunities

BMC Health Services Research, 2019
Background Addiction health service researchers have focused efforts on opioid use disorder (OUD) and strategies to address the emerging public health threats associated with the epidemics of opioid use and opioid overdose.
Kim A. Hoffman, Javier Ponce Terashima, Dennis McCarty   +2 more
doaj   +1 more source

Opioid Epidemics

SSRN Electronic Journal, 2019
In this paper, I propose an economic theory that addresses the epidemic character of opioid epidemics. I consider a community in which individuals are heterogenous with respect to the experience of chronic pain and susceptibility to addiction and live through two periods.
openaire   +5 more sources

Cannabis combined with oxycodone for pain relief in fibromyalgia pain: a randomized clinical self-titration trial with focus on adverse events

Frontiers in Pain Research
ObjectivesWe determined whether adding cannabis to oxycodone for chronic non-cancer pain management could reduce treatment-related adverse effects (AEs) while maintaining effective analgesia.MethodsIn this open-label study, fibromyalgia patients aged ≥18 
Cornelis Jan van Dam, Cornelis Jan van Dam, Cornelis Kramers, Cornelis Kramers, Cornelis Kramers, Arnt Schellekens, Arnt Schellekens, Arnt Schellekens, Arnt Schellekens, Marcel Bouvy, Marcel Bouvy, Eveline van Dorp, Eveline van Dorp, Mikael A. Kowal, Erik Olofsen, Albert Dahan, Albert Dahan, Albert Dahan, Albert Dahan, Marieke Niesters, Marieke Niesters, Marieke Niesters, Monique van Velzen, Monique van Velzen   +23 more
doaj   +1 more source

Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-laboring myometrium [PDF]

, 2013
The existence of opioid receptors in mammalian myometrial tissue is now widely accepted. Previously enkephalin degrading enzymes have been shown to be elevated in pregnant rat uterus and a met-enkephalin analogue has been shown to alter spontaneous ...
McMorrow, Jason P., Carey, Michael F., Campion, Deirdre P., O\u27Connor, J. J., Fanning, Rebecca A., O'Connor, J. J.   +5 more
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Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Forecasting the opioid epidemic [PDF]

Science, 2016
Since 2000, almost half a million Americans have died from drug overdoses. This modern plague—largely driven by opioid addiction—degrades health, saps productivity, spawns crime, and devastates families, all at enormous societal cost. How did we get here, and what do we do now?
openaire   +2 more sources

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

Clinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid, Ahmed I. Soliman, Jordan F. Baye, Natasha J. Petry, Chancellor F. Gray, Rachel A. Myers, Erica N. Elwood, Elizabeth C. Harris, Hrishikesh Chakraborty, Simona Volpi, Renee Rider, Paul R. Dexter, Josh F. Peterson, Todd C. Skaar, Hari K. Parvataneni, Larisa H. Cavallari, Julie A. Johnson, on behalf of the IGNITE Pragmatic Trial Network Investigators, L Orlando, D Voora, C Horowitz, C Horowitz, N Calman, T Skaar, T Skaar, P Dexter, T Skaar, P Dexter, J Johnson, L Cavallari, J Johnson, L Cavallari, J Johnson, L Cavallari, K Blake, K Blake, K Blake, J Peterson, J Peterson, K Cavanaugh, R Singh, R Singh, L Hines, C Wyatt, H Chakraborty, Rishi Chakraborty, Christina Wyatt, Geoff Ginsburg, Kady‐Ann Steen‐Burrell, Bhargav Adagarla, Sarah George, Beth Harris, Jaclyn Holland, Yashika Johnson, Phyllis Kennel, Kristen Linney, Rania Metry, Rachel Myers, Wanda Parker, Gayle Passmore, Carol Pereira, Teji Rakhra‐Burris, Deepak Voora, Ryanne Wu, Teji Rakhra‐Burris, Azita Sadeghpour, Ruth Lehan, Tyffany Locklear, Carol Horowitz, Michelle Ramos, Sabrina Clermont, Bart Ferket, Kenneth Fifer, Diane Hauser, Joseph Kannry, James Murrough, Aniwaa Owusu Obeng, Janet Seo, Tatiana Sabin, Nandini Shroff, Saskia Shuman, Todd Skaar, Paul Dexter, Abi Colwell, Amy Breman, Zeru Desta, Cathy Fulton, Jennelle Hodge, Sheryl Lynch, Jonathan Oliver, Vicky Pratt, Ross Robinson, Elizabeth Rowe, Jennifer Stuart, Emma Tillman, Ashely Vetor, Julie Johnson, Larisa Cavallari, Alexander Parker, Erica Elwood, Kathryn Blake, Emily Cicali, Kelsey Cook, Karam Diaby, Julio Duarte, Ben Duong, Karla Giron, Elizabeth Eddy, Julia Krutov, Carol Mathews, Haesuk Park, Robyn Nelson, Ryan Rhoden, Caroline Schlierle, Taylor Sullivan, Almut Winterstein, Kristen Wiisanen, Josh Peterson, Kerri Cavanaugh, Sara Van Driest, Sara Block, Jordan Baye, Michelle Benck, Chantel Bender, Sylvia Eluhu, Colette Free, Shane Gonnelly, Sarah Hedeen, Lindsay Hines, Steve Houtschilt, Michelle Liu, Salisha Marryshow, Nicole Neville, Natasha Petry, Sidd Pratap, Vernon Sherden, Rajbir Singh, Kimberly Snell. Ana Tomescu, Megan Trietsch, James Walker, Deanna Web, Erin Whiting, Russ Wilke, Simona Volpi, Sarah Hutchison, Natalie Kucher, Ebony Madden, Jessica Reinach, Renee Rider, Ismail Safi, Ella Samer, Lori Orlando, Deepak Voora, Azita Sadeghpour, Lani Banez, Lisa Bendz, Jackie Jordan, Ruth Lehan, Tyffany Locklear, Ann McGee, Christina Nix, Lorraine Vergara, Ryanne Wu, Carol Horowitz, Michelle Ramos, Sabrina Clermont, Tyler Colon, Aaishah Francis, Samantha Guagliardo, Najiba Khan, Camila Tan Lam, Michelle Sciarrino, Emma Maiman‐Stadtmauer, Sofia Medina‐Pardo, Tatiana Sabin, Janet Seo, Lola) Williams, Rishi Chakraborty, Christina Wyatt, Geoff Ginsburg, Sheng Luo, Kady‐Ann Steen‐Burrell, Kevin Anstrom, Bhargav Adagarla, Alicia Ellis, Stephen Ellis, Sarah George, Beth Harris, Jaclyn Holland, Yashika Johnson, Phyllis Kennel, Hwasoon Kim, Kristen Linney, Peter Merrill, Rania Metry, Rachel Myers, Wanda Parker, Gayle Passmore, Carol Pereira, Teji Rakhra‐Burris, Lilin She, Jennifer Shepherd, Saira Siddiqui, Jun Wen, Todd Skaar, Abi Colwell, Brittany Davis, John Howard, Alia Jamison, Lydia Joyner, Ellie Kiihne, Sheryl Lynch, Johnathan Oliver, Ross Robinson, Libbie Silverman, Jordan Sonneville Jennifer Stuart, Laurel Tokar, Ashley Vetor, Neil Calman, Saskia Shuman, Daviana Buck, Nicole Canchucaja Porshia Cook, Ariel Jacobs Danielle John, Samantha Guagliardo, Diane Hauser, Mimi) Milanes, Wambui Ngari, Nandini Shroff, Rajbir Singh, Megan Triestch, Abraham Garcia, Carol Gutierrez, Steven Houtschilt, Maria Lopez, Alan Mejia, Anaite Montes Bu, Deanna Webb, Sonja White, Kathryn Blake, Ben Duong, Taylor Sullivan, Ali Brewer, Kelsey Cook, Brittni Deadrick, Julia Krutov, Lindsay Hines, Jordan Baye, Colette Free, Michelle Benck, Shane Gonnelly, Sarah Hedeen, Alexis Meyer, Blair Svennes, Larisa Cavallari, Erica Elwood, Hana Al Alshaykh, Tala Basha, Emily Cicali, Asia Cobb, Brendon Cooper, Elizabeth Eddy, Amanda Elchynski, Amanda Elsey, Anuksha Gotmare, Karla Giron, Lauren Lemke, Arielle Nelson, Robyn Nelson, Michael Read, Ryan Rhoden, Genevieve Rosier, Isabella Schultz, Chiara Chermont Spina, Joshua Terrell, Alexa Valko, Precious Williams, Tracy Leonard, David Smith, Marian Davis, Vincent Guerra, Jennifer Salo, Claudia Cartaya Torres, Jorge Valedon, Paola Nieves Viana, Alexander Parker, Jose Alonso, Jeffery Gainer, Morgan Howard, Fatoumata Kaba, Brianna Rivers, Liliana Serrano, Kimberly Vigal, ADeia Williams, Josh Peterson, Kerri Cavanaugh, Sara Van Driest, Sara Block, Chantel Bender, Angelo Lazaro, Salisha Merryshow, Nicole Neville, Henry Ong, Erin Whiting   +302 more
wiley   +1 more source

Opioid prescriptions for pain and epidemic of overdose death: can the dramatic reduction in anesthesia mortality serve as an example? [PDF]

, 2016
Igor Kissin Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA Abstract: The annual number of US deaths from prescription-opioid overdose quadrupled between 1999
Kissin, Igor, Kissin I
core   +1 more source