Results 331 to 340 of about 2,542,870 (405)

The μ-opioid receptor differentiates two distinct human nociceptive populations relevant to clinical pain. [PDF]

Cell Rep Med
Staedtler ES, Sapio MR, King DM, Maric D, Ghetti A, Mannes AJ, Iadarola MJ.   +6 more
europepmc   +1 more source

Physical function and perceived pain following inpatient intensive interdisciplinary pain treatment for children and adolescents

PM&R, EarlyView.
Abstract Background Chronic pain among children and adolescents negatively impacts overall functioning and quality of life. Although Intensive Interdisciplinary Pain Treatment (IIPT) programs aim to reduce functional impairment and perceived pain, overall evidence is limited and restricted by small sample sizes and limited diversity in pain diagnoses ...
Mayank Seth, Kate Vieni, Kathryn Hottinger, Katherine Bentley   +3 more
wiley   +1 more source

Profiling the proximal proteome of the activated μ-opioid receptor. [PDF]

Nat Chem Biol
Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R.   +16 more
europepmc   +1 more source

Preoperative spinal education for lumbar spinal stenosis (POSE‐LSS): A qualitative analysis of patient experiences

PM&R, EarlyView.
Abstract Background Surgical intervention for lumbar spinal stenosis (LSS) is common and associated with high rates of postoperative side effects or complications. Prehabilitation programs aim to reduce postoperative complications and enhance outcomes.
James E. Eubanks Jr, Jordan A. Gliedt, Zachary A. Cupler, Geronimo Bejarano, Esther R. C. Janssen, Richard L. Skolasky, Rob J. E. M. Smeets, Michael J. Schneider   +7 more
wiley   +1 more source

Effectiveness of a multimodal physiotherapy program in fighter pilots with flight‐related neck pain: A randomized controlled trial

PM&R, EarlyView.
Abstract Background Flight‐related neck pain constitutes a clinical entity related to the performance, occupational health, and flight safety of fighter pilots. Objective To investigate whether a multimodal physiotherapy program combining supervised motor control exercises with laser‐guided feedback and interferential current therapy with ...
Carlos Fernández‐Morales, Manuel Albornoz‐Cabello, María de los Ángeles Cardero‐Durán, Juan Manuel Moreno‐Vázquez, Luis Espejo‐Antúnez   +4 more
wiley   +1 more source

Delta-opioid receptor signaling alleviates neuropathology and cognitive impairment in the mouse model of Alzheimer's disease by regulating microglia homeostasis and inhibiting HMGB1 pathway. [PDF]

Alzheimers Res Ther
Xu Y, Shao N, Zhi F, Chen R, Yang Y, Li J, Xia Y, Peng Y.   +7 more
europepmc   +1 more source

μ-Opioid Receptor Modulation of the Glutamatergic/GABAergic Midbrain Inputs to the Mouse Dorsal Hippocampus. [PDF]

J Neurosci
Kim HR, Dey S, Sekerkova G, Martina M.
europepmc   +1 more source

Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. [PDF]

Nature
Zhao J, Elgeti M, O'Brien ES, Sár CP, Ei Daibani A, Heng J, Sun X, White E, Che T, Hubbell WL, Kobilka BK, Chen C.   +11 more
europepmc   +1 more source

Synthesis and Biological Evaluation of Novel Biased Mu-Opioid Receptor Agonists. [PDF]

Molecules
Guo Y, Yu R, Zhang T, Ren F, Yu Z, Cheng J, Jia H, Shi W, Zhang Y.   +8 more
europepmc   +1 more source