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The Medical Letter on Drugs and Therapeutics, 2023
Opioid use disorder is a chronic, relapsing disease with physical and psychiatric components. It is associated with economic hardship, social isolation, incarceration, increased rates of blood-borne infections such as HIV and viral hepatitis, adverse pregnancy outcomes, and increased mortality.
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Opioid use disorder is a chronic, relapsing disease with physical and psychiatric components. It is associated with economic hardship, social isolation, incarceration, increased rates of blood-borne infections such as HIV and viral hepatitis, adverse pregnancy outcomes, and increased mortality.
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Polydrug use disorders in individuals with opioid use disorder
Drug and Alcohol Dependence, 2019Understanding the association of polydrug use disorders (PUD) with psychosocial and clinical factors is essential for the treatment of individuals with opioid use disorder (OUD). The aim of this study is to examine whether there is an association between childhood maltreatment, mood disorders, anxiety disorders, personality disorders, or posttraumatic ...
Ahmed N. Hassan +2 more
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Opioid Use Disorder and Perinatal Outcomes
Pediatrics, 2021OBJECTIVES Evidence on the perinatal health of mother-infant dyads affected by opioids is limited. Elevated risks of opioid-related harms for people with opioid use disorder (OUD) increase the urgency to identify protective factors for mothers and infants. Our objectives were to determine perinatal outcomes after an
Bohdan Nosyk +9 more
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The American Journal of Drug and Alcohol Abuse, 2019
Background: While there is growing interest in the possibility that cannabis may be a partial substitute for opioids, studies have yet to examine whether individuals with co-occurring opioid and cannabis use disorders (OUD and CUD) have less risk of negative outcomes than those with OUD only. Objective: This study sought to compare the sociodemographic
Joao P. De Aquino +6 more
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Background: While there is growing interest in the possibility that cannabis may be a partial substitute for opioids, studies have yet to examine whether individuals with co-occurring opioid and cannabis use disorders (OUD and CUD) have less risk of negative outcomes than those with OUD only. Objective: This study sought to compare the sociodemographic
Joao P. De Aquino +6 more
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Methadone for Opioid Use Disorder
2020Methadone is a long-acting full opioid agonist that has a long history in the treatment of opioid use disorder (OUD). It was the first opioid agonist with OUD as an indication for use. Methadone was developed for OUD during a time of prohibition and criminalization of both addiction and the use of opioid agonists for addiction treatment, which resulted
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Clinical Trials for Opioid Use Disorder
2019This chapter describes recent clinical trials for opioid use disorder (OUD), an area that has rapidly accelerated in response to the opioid overdose crisis in the USA and newly appropriated funding. Trials involve a wide range of compounds including cannabinoids and psychedelics, new and existing compounds targeting domains emerging from addiction ...
John Rotrosen +2 more
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Opioid Use Disorder in Physicians
New England Journal of Medicine, 2019Kevin Fiscella +2 more
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Tunable Chemical Disorder in Concentrated Alloys: Defect Physics and Radiation Performance
Chemical Reviews, 2022William J Weber +2 more
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